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    usp8 ubiquitin specific peptidase 8 [ Polypterus senegalus (gray bichir) ]

    Gene ID: 120541320, updated on 8-May-2024

    Summary

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    Gene symbol
    usp8
    Gene description
    ubiquitin specific peptidase 8
    Locus tag
    GTO96_0005977
    See related
    EnsemblRapid:ENSSTSG00000015881
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Polypterus senegalus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Polypteriformes; Polypteridae; Polypterus
    Orthologs
    human zebrafish all
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    Genomic context

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    See usp8 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    100 current ASM1683550v1 (GCF_016835505.1) 12 NC_053165.1 (89142892..89179732)

    Chromosome 12 - NC_053165.1Genomic Context describing neighboring genes Neighboring gene histidine decarboxylase Neighboring gene GA binding protein transcription factor subunit beta 1 Neighboring gene uncharacterized LOC120541321 Neighboring gene uncharacterized LOC120541322

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_053165.1 Chromosome 12 Reference ASM1683550v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K48-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K63-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extrinsic component of endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extrinsic component of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 8
    Names
    UBP8 hydrolase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Polypterus senegalus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1683550v1 Primary Assembly

    Genomic

    1. NC_053165.1 Reference ASM1683550v1 Primary Assembly

      Range
      89142892..89179732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039772822.1 → XP_039628756.1  ubiquitin carboxyl-terminal hydrolase 8 isoform X1

      UniProtKB/TrEMBL
      A0A8X7XN17
      Conserved Domains (2) summary
      COG5560
      Location:736 → 924
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:740 → 1070
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    2. XM_039772821.1 → XP_039628755.1  ubiquitin carboxyl-terminal hydrolase 8 isoform X1

      UniProtKB/TrEMBL
      A0A8X7XN17
      Conserved Domains (2) summary
      COG5560
      Location:736 → 924
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:740 → 1070
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    3. XM_039772825.1 → XP_039628759.1  ubiquitin carboxyl-terminal hydrolase 8 isoform X2

      UniProtKB/TrEMBL
      A0A8X7XN17
      Related
      ENSSTSP00000036186.1, ENSSTST00000040687.1
      Conserved Domains (2) summary
      COG5560
      Location:736 → 923
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:740 → 1069
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    4. XM_039772823.1 → XP_039628757.1  ubiquitin carboxyl-terminal hydrolase 8 isoform X1

      UniProtKB/TrEMBL
      A0A8X7XN17
      Conserved Domains (2) summary
      COG5560
      Location:736 → 924
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:740 → 1070
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    5. XM_039772824.1 → XP_039628758.1  ubiquitin carboxyl-terminal hydrolase 8 isoform X1

      UniProtKB/TrEMBL
      A0A8X7XN17
      Conserved Domains (2) summary
      COG5560
      Location:736 → 924
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:740 → 1070
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    Nucleotide Protein
    Heading Accession and Version

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