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    SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 [ Passer montanus (Eurasian tree sparrow) ]

    Gene ID: 120514173, updated on 3-Aug-2024

    Summary

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    Gene symbol
    SRGAP3
    Gene description
    SLIT-ROBO Rho GTPase activating protein 3
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Passer montanus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Passeroidea; Passeridae; Passer
    Orthologs
    human mouse all
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    Genomic context

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    See SRGAP3 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    100 current ASM1480565v1 (GCF_014805655.1) Unplaced Scaffold NW_024374367.1 (16741892..16818213, complement)

    NW_024374367.1Genomic Context describing neighboring genes Neighboring gene oxytocin receptor Neighboring gene RAD18 E3 ubiquitin protein ligase Neighboring gene THUMP domain containing 3 Neighboring gene von Hippel-Lindau tumor suppressor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_024374367 Unplaced Scaffold Reference ASM1480565v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SLIT-ROBO Rho GTPase-activating protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Passer montanus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1480565v1 Primary Assembly

    Genomic

    1. NW_024374367.1 Reference ASM1480565v1 Primary Assembly

      Range
      16741892..16818213 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039734387.1 → XP_039590321.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X7

      Conserved Domains (3) summary
      cd07684
      Location:26 → 278
      F-BAR_srGAP3; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 3
      cd11955
      Location:724 → 776
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:481 → 665
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...

    2. XM_039734386.1 → XP_039590320.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X6

      Conserved Domains (3) summary
      cd07684
      Location:26 → 278
      F-BAR_srGAP3; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 3
      cd11955
      Location:748 → 800
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:502 → 689
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...

    3. XM_039734385.1 → XP_039590319.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X5

      Conserved Domains (3) summary
      cd11955
      Location:561 → 613
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:318 → 502
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:1 → 115
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    4. XM_039734384.1 → XP_039590318.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X4

      Conserved Domains (3) summary
      cd11955
      Location:564 → 616
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:318 → 502
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:1 → 115
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    5. XM_039734382.1 → XP_039590316.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X2

      Conserved Domains (3) summary
      cd11955
      Location:588 → 640
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:339 → 526
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:1 → 115
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    6. XM_039734381.1 → XP_039590315.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X1

      Conserved Domains (3) summary
      cd11955
      Location:588 → 640
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:339 → 526
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:1 → 115
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    7. XM_039734383.1 → XP_039590317.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X3

      Conserved Domains (3) summary
      cd11955
      Location:585 → 637
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:339 → 526
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:1 → 115
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    Nucleotide Protein
    Heading Accession and Version

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