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    LOC120085536 1-phosphatidylinositol-3-phosphate 5-kinase FAB1B [ Benincasa hispida (wax gourd) ]

    Gene ID: 120085536, updated on 7-Dec-2023

    Summary

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    Gene symbol
    LOC120085536
    Gene description
    1-phosphatidylinositol-3-phosphate 5-kinase FAB1B
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Benincasa hispida
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Benincasa
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    Genomic context

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    See LOC120085536 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    100 current ASM972705v1 (GCF_009727055.1) 9 NC_052357.1 (5567944..5578584, complement)

    Chromosome 9 - NC_052357.1Genomic Context describing neighboring genes Neighboring gene alanine aminotransferase 2, mitochondrial Neighboring gene uncharacterized LOC120085537 Neighboring gene translation initiation factor eIF-2B subunit alpha Neighboring gene FCS-Like Zinc finger 17-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_052357.1 Chromosome 9 Reference ASM972705v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-phosphate 5-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol-3-phosphate 5-kinase FAB1B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Benincasa hispida Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM972705v1

    Genomic

    1. NC_052357.1 Reference ASM972705v1

      Range
      5567944..5578584 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039041556.1 → XP_038897484.1  1-phosphatidylinositol-3-phosphate 5-kinase FAB1B isoform X1

      Conserved Domains (3) summary
      cd03334
      Location:383 → 655
      Fab1_TCP; TCP-1 like domain of the eukaryotic phosphatidylinositol 3-phosphate (PtdIns3P) 5-kinase Fab1. Fab1p is important for vacuole size regulation, presumably by modulating PtdIns(3,5)P2 effector activity. In the human homolog p235/PIKfyve deletion of this ...
      cd15725
      Location:32 → 99
      FYVE_PIKfyve_Fab1; FYVE domain found in metazoan PIKfyve, fungal and plant Fab1, and similar proteins
      cd17300
      Location:1520 → 1782
      PIPKc_PIKfyve; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in 1-phosphatidylinositol-3-phosphate 5-kinase and similar proteins

    2. XM_039041557.1 → XP_038897485.1  1-phosphatidylinositol-3-phosphate 5-kinase FAB1B isoform X2

      Conserved Domains (3) summary
      cd03334
      Location:383 → 655
      Fab1_TCP; TCP-1 like domain of the eukaryotic phosphatidylinositol 3-phosphate (PtdIns3P) 5-kinase Fab1. Fab1p is important for vacuole size regulation, presumably by modulating PtdIns(3,5)P2 effector activity. In the human homolog p235/PIKfyve deletion of this ...
      cl28890
      Location:32 → 99
      FYVE_like_SF; FYVE domain like superfamily
      cd17300
      Location:1512 → 1774
      PIPKc_PIKfyve; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in 1-phosphatidylinositol-3-phosphate 5-kinase and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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