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    SIN3A SIN3 transcription regulator family member A [ Canis lupus familiaris (dog) ]

    Gene ID: 478372, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SIN3Aprovided by VGNC
    Official Full Name
    SIN3 transcription regulator family member Aprovided by VGNC
    Primary source
    VGNC:VGNC:46177
    See related
    Ensembl:ENSCAFG00845020249
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See SIN3A in Genome Data Viewer
    Location:
    chromosome: 30
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (38436823..38512188, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (38162224..38237534, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (38670990..38745906, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (38389129..38464067, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (38434094..38509422, complement)

    Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene nei like DNA glycosylase 1 Neighboring gene microRNA mir-631 Neighboring gene mannosidase alpha class 2C member 1 Neighboring gene uncharacterized LOC111093280 Neighboring gene uncharacterized LOC119866946 Neighboring gene protein tyrosine phosphatase non-receptor type 9 Neighboring gene snurportin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    paired amphipathic helix protein Sin3a
    Names
    SIN3 homolog A, transcription regulator
    SIN3 transcription regulator homolog A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051834.1 Reference ROS_Cfam_1.0

      Range
      38436823..38512188 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038443002.1 → XP_038298930.1  paired amphipathic helix protein Sin3a

      UniProtKB/TrEMBL
      A0A8C0JR57, A0A8C0TBX5, A0A8C0THK6, A0A8I3PCR3
      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    2. XM_038443001.1 → XP_038298929.1  paired amphipathic helix protein Sin3a

      UniProtKB/TrEMBL
      A0A8C0JR57, A0A8C0TBX5, A0A8C0THK6, A0A8I3PCR3
      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    3. XM_038443000.1 → XP_038298928.1  paired amphipathic helix protein Sin3a

      UniProtKB/TrEMBL
      A0A8C0JR57, A0A8C0TBX5, A0A8C0THK6, A0A8I3PCR3
      Related
      ENSCAFP00845027945.1, ENSCAFT00845035718.1
      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049290.1 Alternate UMICH_Zoey_3.1

      Range
      38389129..38464067 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038517428.1 → XP_038373356.1  paired amphipathic helix protein Sin3a

      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    2. XM_038517427.1 → XP_038373355.1  paired amphipathic helix protein Sin3a

      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    3. XM_038517426.1 → XP_038373354.1  paired amphipathic helix protein Sin3a

      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

      Range
      38434094..38509422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038645406.1 → XP_038501334.1  paired amphipathic helix protein Sin3a

      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    2. XM_038645404.1 → XP_038501332.1  paired amphipathic helix protein Sin3a

      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    3. XM_038645403.1 → XP_038501331.1  paired amphipathic helix protein Sin3a

      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

      Range
      38670990..38745906 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038581035.1 → XP_038436963.1  paired amphipathic helix protein Sin3a

      UniProtKB/TrEMBL
      A0A8C0JR57, A0A8C0TBX5, A0A8C0THK6, A0A8I3PCR3
      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    2. XM_038581034.1 → XP_038436962.1  paired amphipathic helix protein Sin3a

      UniProtKB/TrEMBL
      A0A8C0JR57, A0A8C0TBX5, A0A8C0THK6, A0A8I3PCR3
      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    3. XM_038581033.1 → XP_038436961.1  paired amphipathic helix protein Sin3a

      UniProtKB/TrEMBL
      A0A8C0JR57, A0A8C0TBX5, A0A8C0THK6, A0A8I3PCR3
      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      38162224..38237534 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014109583.3 → XP_013965058.2  paired amphipathic helix protein Sin3a

      UniProtKB/TrEMBL
      A0A8C0JR57, A0A8C0TBX5, A0A8C0THK6, A0A8I3PCR3
      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    2. XM_038461289.1 → XP_038317217.1  paired amphipathic helix protein Sin3a

      UniProtKB/TrEMBL
      A0A8C0JR57, A0A8C0TBX5, A0A8C0THK6, A0A8I3PCR3
      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

    3. XM_038461288.1 → XP_038317216.1  paired amphipathic helix protein Sin3a

      UniProtKB/TrEMBL
      A0A8C0JR57, A0A8C0TBX5, A0A8C0THK6, A0A8I3PCR3
      Conserved Domains (1) summary
      COG5602
      Location:5 → 1214
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]
    Nucleotide Protein
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