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    TJP2 tight junction protein 2 [ Molossus molossus (Pallas's mastiff bat) ]

    Gene ID: 118629764, updated on 30-Mar-2024

    Summary

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    Gene symbol
    TJP2
    Gene description
    tight junction protein 2
    Locus tag
    HJG59_008877
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Molossus molossus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Molossidae; Molossus
    Orthologs
    human mouse all
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    Genomic context

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    See TJP2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    100 current mMolMol1.p (GCF_014108415.1) Unplaced Scaffold NW_023425349.1 (51589910..51689604, complement)

    NW_023425349.1Genomic Context describing neighboring genes Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene ragulator complex protein LAMTOR5-like Neighboring gene small nucleolar RNA SNORA32 Neighboring gene frataxin Neighboring gene coiled-coil domain-containing protein 115-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023425349 Unplaced Scaffold Reference mMolMol1.p

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell junction organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment of endothelial intestinal barrier IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of blood-brain barrier permeability IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tight junction protein ZO-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Molossus molossus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mMolMol1.p

    Genomic

    1. NW_023425349.1 Reference mMolMol1.p

      Range
      51589910..51689604 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036261389.1 → XP_036117282.1  tight junction protein ZO-2 isoform X2

      UniProtKB/TrEMBL
      A0A7J8EE90
      Conserved Domains (5) summary
      cd12027
      Location:675 → 737
      SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
      smart00072
      Location:771 → 950
      GuKc; Guanylate kinase homologues
      smart00228
      Location:381 → 458
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:91 → 176
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      TIGR01642
      Location:216 → 301
      U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

    2. XM_036261388.1 → XP_036117281.1  tight junction protein ZO-2 isoform X1

      UniProtKB/TrEMBL
      A0A7J8EEM6, A0A7J8EET4
      Conserved Domains (5) summary
      cd12027
      Location:675 → 737
      SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
      smart00072
      Location:771 → 950
      GuKc; Guanylate kinase homologues
      smart00228
      Location:381 → 458
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:91 → 176
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      TIGR01642
      Location:216 → 301
      U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

    3. XM_036261390.1 → XP_036117283.1  tight junction protein ZO-2 isoform X3

      UniProtKB/TrEMBL
      A0A7J8EEQ1, A0A7J8EET4
      Conserved Domains (5) summary
      cd12027
      Location:616 → 678
      SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
      smart00072
      Location:712 → 891
      GuKc; Guanylate kinase homologues
      smart00228
      Location:322 → 399
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:32 → 117
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      TIGR01642
      Location:157 → 242
      U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

    4. XM_036261391.1 → XP_036117284.1  tight junction protein ZO-2 isoform X4

      UniProtKB/TrEMBL
      A0A7J8EET4
      Conserved Domains (5) summary
      cd12027
      Location:593 → 655
      SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
      smart00072
      Location:689 → 868
      GuKc; Guanylate kinase homologues
      smart00228
      Location:299 → 376
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:9 → 94
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      TIGR01642
      Location:134 → 219
      U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    Nucleotide Protein
    Heading Accession and Version

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