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    LOC118517627 ecdysone receptor [ Anopheles stephensi (Asian malaria mosquito) ]

    Gene ID: 118517627, updated on 19-Jun-2024

    Summary

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    Gene symbol
    LOC118517627
    Gene description
    ecdysone receptor
    See related
    VectorBase:ASTEI20_034656
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles stephensi
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
    Orthologs
    fruit fly all
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    Genomic context

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    See LOC118517627 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    100 current UCI_ANSTEP_V1.0 (GCF_013141755.1) 2 NC_050202.1 (2956043..3109158, complement)

    Chromosome 2 - NC_050202.1Genomic Context describing neighboring genes Neighboring gene formin-J-like Neighboring gene uncharacterized LOC118504722 Neighboring gene glycosyltransferase 25 family member Neighboring gene uncharacterized LOC118517638 Neighboring gene uncharacterized protein C16orf52 homolog A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_050202.1 Chromosome 2 Reference UCI_ANSTEP_V1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ecdysone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ecdysone receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ecdysone receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Anopheles stephensi Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCI_ANSTEP_V1.0

    Genomic

    1. NC_050202.1 Reference UCI_ANSTEP_V1.0

      Range
      2956043..3109158 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036063937.1 → XP_035919830.1  ecdysone receptor isoform X1

      Conserved Domains (4) summary
      cd06938
      Location:479 → 712
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:327 → 417
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers
      PRK12688
      Location:92 → 157
      PRK12688; flagellin; Reviewed
      COG5422
      Location:227 → 318
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]

    2. XM_036063938.1 → XP_035919831.1  ecdysone receptor isoform X2

      Conserved Domains (2) summary
      cd06938
      Location:358 → 591
      NR_LBD_EcR; The ligand binding domain (LBD) of the Ecdysone receptor, a member of the nuclear receptors super family
      cd07161
      Location:206 → 296
      NR_DBD_EcR; DNA-binding domain of Ecdysone receptor (ECR) family is composed of two C4-type zinc fingers
    Nucleotide Protein Strain
    Heading Accession and Version

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