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    BANP BTG3 associated nuclear protein [ Homo sapiens (human) ]

    Gene ID: 54971, updated on 2-May-2024

    Summary

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    Official Symbol
    BANPprovided by HGNC
    Official Full Name
    BTG3 associated nuclear proteinprovided by HGNC
    Primary source
    HGNC:HGNC:13450
    See related
    Ensembl:ENSG00000172530 MIM:611564; AllianceGenome:HGNC:13450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BEND1; SMAR1; SMARBP1
    Summary
    This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
    Expression
    Ubiquitous expression in testis (RPKM 1.3), spleen (RPKM 1.1) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    Location:
    16q24.2
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (87949238..88077318)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (94021837..94148506)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (87982844..88110924)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:87931441-87932140 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11343 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11344 Neighboring gene carbonic anhydrase 5A Neighboring gene small EDRK-rich factor 1-like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:87979603-87980148 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11345 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:87984965-87985607 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11346 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:87990141-87991083 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88000587-88001090 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88008279-88008799 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88016725-88017317 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88033523-88034377 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88034378-88035231 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88039157-88039702 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88039703-88040246 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr16:88042893-88043606 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr16:88042179-88042892 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88046491-88047404 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88047405-88048317 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:88058223-88058469 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88060746-88061316 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88064237-88064738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88069223-88069723 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88078499-88079000 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88096566-88097334 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88098057-88098732 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88099409-88100084 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11348 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11349 Neighboring gene uncharacterized LOC124903754 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88123859-88124486 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88126373-88127000 Neighboring gene uncharacterized LOC400553 Neighboring gene zinc finger protein 469

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural insights into DNA recognition by the BEN domain of the transcription factor BANP. Liu K, et al. J Biol Chem, 2023 Jun. PMID 37086783, Free PMC Article
    2. SMAR1 repression by pluripotency factors and consequent chemoresistance in breast cancer stem-like cells is reversed by aspirin. Bhattacharya A, et al. Sci Signal, 2020 Oct 20. PMID 33082288
    3. SMAR1 favors immunosurveillance of cancer cells by modulating calnexin and MHC I expression. Alam A, et al. Neoplasia, 2019 Oct. PMID 31422285, Free PMC Article
    4. Circular BANP, an upregulated circular RNA that modulates cell proliferation in colorectal cancer. Zhu M, et al. Biomed Pharmacother, 2017 Apr. PMID 28103507
    5. Gene regulation by SMAR1: Role in cellular homeostasis and cancer. Malonia SK, et al. Biochim Biophys Acta, 2011 Jan. PMID 20709157

    See all (70) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BANP Participates in the Chronic Intermittent Hypoxia-Induced Senescence of Vascular Endothelial Cells by Promoting P53 Phosphorylation and Nuclear Retention.
      Title: BANP Participates in the Chronic Intermittent Hypoxia-Induced Senescence of Vascular Endothelial Cells by Promoting P53 Phosphorylation and Nuclear Retention.
    2. Nuclear Matrix-associated Protein SMAR1 Attenuated Acute Graft-versus-host Disease by Targeting JAK-STAT Signaling in CD4 + T Cells.
      Title: Nuclear Matrix-associated Protein SMAR1 Attenuated Acute Graft-versus-host Disease by Targeting JAK-STAT Signaling in CD4 + T Cells.
    3. ZNF471 Interacts with BANP to Reduce Tumour Malignancy by Inactivating PI3K/AKT/mTOR Signalling but is Frequently Silenced by Aberrant Promoter Methylation in Renal Cell Carcinoma.
      Title: ZNF471 Interacts with BANP to Reduce Tumour Malignancy by Inactivating PI3K/AKT/mTOR Signalling but is Frequently Silenced by Aberrant Promoter Methylation in Renal Cell Carcinoma.
    4. Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
      Title: Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
    5. SMAR1 repression by pluripotency factors and consequent chemoresistance in breast cancer stem-like cells is reversed by aspirin.
      Title: SMAR1 repression by pluripotency factors and consequent chemoresistance in breast cancer stem-like cells is reversed by aspirin.
    6. BANP opens chromatin and activates CpG-island-regulated genes.
      Title: BANP opens chromatin and activates CpG-island-regulated genes.
    7. our observations establish that increased expression of SMAR1 in cancers can positively regulate MHC I surface expression thereby leading to higher chances of tumor regression and elimination of cancer cells.
      Title: SMAR1 favors immunosurveillance of cancer cells by modulating calnexin and MHC I expression.
    8. Cdc20 functions as an important negative regulator of SMAR1 in higher grades of cancer
      Title: Cdc20 directs proteasome-mediated degradation of the tumor suppressor SMAR1 in higher grades of cancer through the anaphase promoting complex.
    9. Dysregulated circ-BANP appears to have an important role in colorectal cancer cells.
      Title: Circular BANP, an upregulated circular RNA that modulates cell proliferation in colorectal cancer.
    10. results reveal the complex molecular mechanism underlying SMAR1-mediated signal-dependent and -independent regulation of alternative splicing via Sam68 deacetylation
      Title: Nuclear matrix-associated protein SMAR1 regulates alternative splicing via HDAC6-mediated deacetylation of Sam68.
    Submit: New GeneRIF Correction See all GeneRIFs (30)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
    EBI GWAS Catalog
    Loci at chromosomes 13, 19 and 20 influence age at natural menopause.
    EBI GWAS Catalog
    New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    HIV-1 interactions

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    Protein interactions

    Protein Gene Interaction Pubs
    Tat tat SMAR1 recruits HDAC1-Sin3 corepressor complex to remodel chromatin structure at HIV-1 LTR. Overexpression of SMAR1 leads to reduction in LTR-mediated transcription in a Tat dependent and independent manner, resulting in a decreased virion production PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ10177, FLJ20538, DKFZp761H172

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nuclear body IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  

    General protein information

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    Preferred Names
    protein BANP
    Names
    BEN domain-containing protein 1
    scaffold/matrix-associated region-1-binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029918.1 RefSeqGene

      Range
      5003..130885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001173539.2 → NP_001167010.1  protein BANP isoform c

      See identical proteins and their annotated locations for NP_001167010.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) represents use of an alternate promoter and 5' UTR, uses one alternate in-frame splices site, and lacks one alternate in-frame exon in the coding region, compared to variant 7. The resulting isoform (c) differs at two internal regions, compared to isoform g. Variants 3 and 9-11 all encode the same isoform (c).
      Source sequence(s)
      AK001039, AK125232, AK293472, AL157429
      Consensus CDS
      CCDS92204.1
      UniProtKB/TrEMBL
      B3KM38, B4DE54
      Related
      ENSP00000515015.1, ENST00000700483.1
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    2. NM_001173540.2 → NP_001167011.1  protein BANP isoform d

      See identical proteins and their annotated locations for NP_001167011.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) represents use of an alternate promoter and 5' UTR, uses three alternate in-frame splices sites, and lacks one alternate in-frame exon in the coding region, compared to variant 7. The resulting isoform (d) differs at four internal regions, compared to isoform g.
      Source sequence(s)
      AK001039, AK125232, AK297945, AL157429
      Consensus CDS
      CCDS54055.1
      UniProtKB/TrEMBL
      B3KM38
      Related
      ENSP00000487304.1, ENST00000626016.2
      Conserved Domains (1) summary
      smart01025
      Location:224 → 297
      BEN; The BEN domain is found in diverse animal proteins

    3. NM_001173541.2 → NP_001167012.1  protein BANP isoform e

      See identical proteins and their annotated locations for NP_001167012.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) represents use of an alternate promoter and 5' UTR, uses one alternate in-frame splices site, and lacks two alternate in-frame exons in the coding region, compared to variant 7. The resulting isoform (e) differs at three internal regions, compared to isoform g. Variants 5 and 12-14 all encode the same isoform (e).
      Source sequence(s)
      AK001039, AK297945, AK315089, AL157429
      Consensus CDS
      CCDS54053.1
      UniProtKB/TrEMBL
      B3KM38
      Related
      ENSP00000432508.1, ENST00000479780.6
      Conserved Domains (1) summary
      smart01025
      Location:218 → 291
      BEN; The BEN domain is found in diverse animal proteins

    4. NM_001173542.1 → NP_001167013.1  protein BANP isoform f

      See identical proteins and their annotated locations for NP_001167013.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) represents use of an alternate promoter and 5' UTR, uses two alternate in-frame splices site, and lacks one alternate in-frame exon in the coding region, compared to variant 7. The resulting isoform (f) differs at three internal regions, compared to isoform g. Variants 6 and 15-17 all encode the same isoform (f).
      Source sequence(s)
      AK293472, AK297945, AK315535, AL157429
      Consensus CDS
      CCDS54052.1
      UniProtKB/TrEMBL
      A0A0S2Z5M2, B3KM38
      Related
      ENSP00000444352.1, ENST00000538234.5
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    5. NM_001173543.1 → NP_001167014.1  protein BANP isoform g

      See identical proteins and their annotated locations for NP_001167014.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) represents the longest transcript and encodes the longest isoform (g).
      Source sequence(s)
      AC127455, AK001039, AK094158, AK125232, AL157429
      Consensus CDS
      CCDS54054.1
      UniProtKB/Swiss-Prot
      A8MU25, A8MX25, B2RCF7, B4DNJ9, F5GZM0, Q8N9N5, Q96GJ7, Q9NWY1
      UniProtKB/TrEMBL
      B3KM38
      Related
      ENSP00000376902.1, ENST00000393207.5
      Conserved Domains (1) summary
      smart01025
      Location:249 → 322
      BEN; The BEN domain is found in diverse animal proteins

    6. NM_001384916.1 → NP_001371845.1  protein BANP isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8), as well as variant 1, encodes isoform a.
      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS42215.1
      UniProtKB/TrEMBL
      A0A0S2Z5C2, B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:218 → 291
      BEN; The BEN domain is found in diverse animal proteins

    7. NM_001384918.1 → NP_001371847.1  protein BANP isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9), as well as variants 3, 10, and 11, encodes isoform c.
      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS92204.1
      UniProtKB/TrEMBL
      B3KM38, B4DE54
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    8. NM_001384919.1 → NP_001371848.1  protein BANP isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10), as well as variants 3, 9, and 11, encodes isoform c.
      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS92204.1
      UniProtKB/TrEMBL
      B3KM38, B4DE54
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    9. NM_001384920.1 → NP_001371849.1  protein BANP isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11), as well as variants 3, 9, and 10, encodes isoform c.
      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS92204.1
      UniProtKB/TrEMBL
      B3KM38, B4DE54
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    10. NM_001384921.1 → NP_001371850.1  protein BANP isoform e

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12), as well as variants 5, 13, and 14, encodes isoform e.
      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS54053.1
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:218 → 291
      BEN; The BEN domain is found in diverse animal proteins

    11. NM_001384922.1 → NP_001371851.1  protein BANP isoform e

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13), as well as variants 5, 12, and 14, encodes isoform e.
      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS54053.1
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:218 → 291
      BEN; The BEN domain is found in diverse animal proteins

    12. NM_001384923.1 → NP_001371852.1  protein BANP isoform e

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14), as well as variants 5, 12, and 13, encodes isoform e.
      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS54053.1
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:218 → 291
      BEN; The BEN domain is found in diverse animal proteins

    13. NM_001384925.1 → NP_001371854.1  protein BANP isoform f

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15), as well as variants 6, 16, and 17, encodes isoform f.
      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS54052.1
      UniProtKB/TrEMBL
      A0A0S2Z5M2, B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    14. NM_001384926.1 → NP_001371855.1  protein BANP isoform f

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16), as well as variants 6, 15, and 17, encodes isoform f.
      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS54052.1
      UniProtKB/TrEMBL
      A0A0S2Z5M2, B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    15. NM_001384927.1 → NP_001371856.1  protein BANP isoform f

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17), as well as variants 6, 15, and 16, encodes isoform f.
      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS54052.1
      UniProtKB/TrEMBL
      A0A0S2Z5M2, B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    16. NM_001384928.1 → NP_001371857.1  protein BANP isoform h

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18), as well as variant 19, encodes isoform h.
      Source sequence(s)
      AC127455, AC134312
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:263 → 336
      BEN; The BEN domain is found in diverse animal proteins

    17. NM_001384929.1 → NP_001371858.1  protein BANP isoform h

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19), as well as variant 18, encodes isoform h.
      Source sequence(s)
      AC127455, AC134312
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:263 → 336
      BEN; The BEN domain is found in diverse animal proteins

    18. NM_001384931.1 → NP_001371860.1  protein BANP isoform i

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20), as well as variant 21, encodes isoform i.
      Source sequence(s)
      AC127455, AC134312
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:263 → 336
      BEN; The BEN domain is found in diverse animal proteins

    19. NM_001384935.1 → NP_001371864.1  protein BANP isoform i

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21), as well as variant 20, encodes isoform i.
      Source sequence(s)
      AC127455, AC134312
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:263 → 336
      BEN; The BEN domain is found in diverse animal proteins

    20. NM_001384936.1 → NP_001371865.1  protein BANP isoform j

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22), as well as variant 23, encodes isoform j.
      Source sequence(s)
      AC127455, AC134312
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:224 → 297
      BEN; The BEN domain is found in diverse animal proteins

    21. NM_001384937.1 → NP_001371866.1  protein BANP isoform j

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23), as well as variant 22, encodes isoform j.
      Source sequence(s)
      AC127455, AC134312
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:224 → 297
      BEN; The BEN domain is found in diverse animal proteins

    22. NM_001384938.1 → NP_001371867.1  protein BANP isoform k

      Status: REVIEWED

      Source sequence(s)
      AC127455, AC134312
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:224 → 297
      BEN; The BEN domain is found in diverse animal proteins

    23. NM_001384939.1 → NP_001371868.1  protein BANP isoform l

      Status: REVIEWED

      Description
      Transcript Variant: This variant (25), as well as variant 26, encodes isoform l.
      Source sequence(s)
      AC127455, AC134312
      Conserved Domains (1) summary
      smart01025
      Location:154 → 227
      BEN; The BEN domain is found in diverse animal proteins

    24. NM_001384940.1 → NP_001371869.1  protein BANP isoform l

      Status: REVIEWED

      Description
      Transcript Variant: This variant (26), as well as variant 25, encodes isoform l.
      Source sequence(s)
      AC127455, AC134312
      Conserved Domains (1) summary
      smart01025
      Location:154 → 227
      BEN; The BEN domain is found in diverse animal proteins

    25. NM_001384941.1 → NP_001371870.1  protein BANP isoform m

      Status: REVIEWED

      Description
      Transcript Variant: This variant (27), as well as variant 28, encodes isoform m.
      Source sequence(s)
      AC127455, AC134312
      Conserved Domains (1) summary
      smart01025
      Location:154 → 227
      BEN; The BEN domain is found in diverse animal proteins

    26. NM_001384942.1 → NP_001371871.1  protein BANP isoform m

      Status: REVIEWED

      Description
      Transcript Variant: This variant (28), as well as variant 27, encodes isoform m.
      Source sequence(s)
      AC127455, AC134312
      Conserved Domains (1) summary
      smart01025
      Location:154 → 227
      BEN; The BEN domain is found in diverse animal proteins

    27. NM_001384943.1 → NP_001371872.1  protein BANP isoform n

      Status: REVIEWED

      Source sequence(s)
      AC127455, AC134312
      Conserved Domains (1) summary
      smart01025
      Location:115 → 188
      BEN; The BEN domain is found in diverse animal proteins

    28. NM_001384944.1 → NP_001371873.1  protein BANP isoform o

      Status: REVIEWED

      Source sequence(s)
      AC127455, AC134312
      Conserved Domains (1) summary
      smart01025
      Location:115 → 188
      BEN; The BEN domain is found in diverse animal proteins

    29. NM_001386991.1 → NP_001373920.1  protein BANP isoform p

      Status: REVIEWED

      Source sequence(s)
      AC127455, AC134312
      Consensus CDS
      CCDS92203.1
      UniProtKB/TrEMBL
      A0A804HKG3, B3KM38
      Related
      ENSP00000507916.1, ENST00000682872.1
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    30. NM_001386992.1 → NP_001373921.1  protein BANP isoform q

      Status: REVIEWED

      Source sequence(s)
      AC127455, AC134312
      UniProtKB/TrEMBL
      B3KM38
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    31. NM_001424170.1 → NP_001411099.1  protein BANP isoform c

      Status: REVIEWED

      Source sequence(s)
      CP068262
      UniProtKB/TrEMBL
      B4DE54

    32. NM_017869.4 → NP_060339.2  protein BANP isoform a

      See identical proteins and their annotated locations for NP_060339.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents use of an alternate promoter and 5' UTR, uses two alternate in-frame splices sites, and lacks two alternate in-frame exons in the coding region, compared to variant 7. The resulting isoform (a) differs at four internal regions, compared to isoform g. Variants 1 and 8 both encode the same isoform (a).
      Source sequence(s)
      AK000545, AK001039, BC009424, CN289917, DA632793, T49823
      Consensus CDS
      CCDS42215.1
      UniProtKB/TrEMBL
      A0A0S2Z5C2, B3KM38
      Related
      ENSP00000347125.4, ENST00000355022.8
      Conserved Domains (1) summary
      smart01025
      Location:218 → 291
      BEN; The BEN domain is found in diverse animal proteins

    33. NM_079837.3 → NP_524576.2  protein BANP isoform b

      See identical proteins and their annotated locations for NP_524576.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) represents use of an alternate promoter and 5' UTR, uses two alternate in-frame splices sites, and lacks one alternate in-frame exon in the coding region, compared to variant 7. The resulting isoform (b) differs at three internal regions, compared to isoform g.
      Source sequence(s)
      AK001039, AK125232, CN289917
      Consensus CDS
      CCDS10966.2
      UniProtKB/TrEMBL
      B3KM38
      Related
      ENSP00000376903.2, ENST00000393208.6
      Conserved Domains (1) summary
      smart01025
      Location:218 → 291
      BEN; The BEN domain is found in diverse animal proteins

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      87949238..88077318
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      94021837..94148506
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8N9N5.3 GenPept UniProtKB/Swiss-Prot:Q8N9N5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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