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    TPH1 tryptophan hydroxylase 1 [ Pantherophis guttatus ]

    Gene ID: 117665266, updated on 19-Mar-2024

    Summary

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    Gene symbol
    TPH1
    Gene description
    tryptophan hydroxylase 1
    See related
    EnsemblRapid:ENSPGUG00005005986
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pantherophis guttatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Colubrinae; Pantherophis
    Orthologs
    human mouse all
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    Genomic context

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    See TPH1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_10 current CU_Pguttatus_1 (GCF_029531705.1) Unplaced Scaffold NW_026844021.1 (66484654..66505001, complement)
    100 previous assembly UNIGE_PanGut_3.0 (GCF_001185365.1) Unplaced Scaffold NW_023010720.1 (8284761..8305070)

    NW_026844021.1Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel subfamily C member 1 Neighboring gene uncharacterized LOC132710724 Neighboring gene secretion regulating guanine nucleotide exchange factor Neighboring gene serum amyloid A like 1 Neighboring gene HPS5 biogenesis of lysosomal organelles complex 2 subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tryptophan 5-monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in aromatic amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in serotonin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tryptophan 5-hydroxylase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_029531705.1-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CU_Pguttatus_1

    Genomic

    1. NW_026844021.1 Reference CU_Pguttatus_1

      Range
      66484654..66505001 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_034416948.2 → XP_034272839.1  tryptophan 5-hydroxylase 1

      UniProtKB/TrEMBL
      A0A6P9BSC7
      Related
      ENSPGUP00005008279.1
      Conserved Domains (1) summary
      TIGR01270
      Location:62 → 481
      Trp_5_monoox; tryptophan 5-monooxygenase, tetrameric
    Nucleotide Protein
    Heading Accession and Version

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