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    algn-6 putative dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 182392, updated on 18-Sep-2024

    Summary

    Official Symbol
    algn-6
    Official Full Name
    putative dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
    Primary source
    WormBase:WBGene00007435
    Locus tag
    CELE_C08B11.8
    See related
    AllianceGenome:WB:WBGene00007435
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process and protein N-linked glycosylation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ic. Orthologous to human ALG6 (ALG6 alpha-1,3-glucosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See algn-6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (8040004..8041732)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Actin-like protein C08B11.6 Neighboring gene Uncharacterized protein Neighboring gene Ubiquitin carboxyl-terminal hydrolase ubh-4 Neighboring gene Ubiquitin carboxyl-terminal hydrolase 47 Neighboring gene Apurinic-apyrimidinic endonuclease Neighboring gene Male Tail tip Retraction Expression

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in dolichol-linked oligosaccharide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein N-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    putative dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
    NP_495685.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8040004..8041732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063284.4NP_495685.1  putative dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495685.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09226
      Conserved Domains (1) summary
      pfam03155
      Location:74490
      Alg6_Alg8; ALG6, ALG8 glycosyltransferase family