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    cdk12 cyclin-dependent kinase 12 [ Gadus morhua (Atlantic cod) ]

    Gene ID: 115538999, updated on 17-Mar-2024

    Summary

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    Gene symbol
    cdk12
    Gene description
    cyclin-dependent kinase 12
    See related
    Ensembl:ENSGMOG00000000133
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gadus morhua
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Gadidae; Gadus
    Orthologs
    human zebrafish all
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    Genomic context

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    See cdk12 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    100 current gadMor3.0 (GCF_902167405.1) 2 NC_044049.1 (12918797..12939890)

    Chromosome 2 - NC_044049.1Genomic Context describing neighboring genes Neighboring gene SH3 and cysteine rich domain 2 Neighboring gene F-box and leucine-rich repeat protein 20 Neighboring gene neuronal differentiation 2 Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 1B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_044049.1 Chromosome 2 Reference gadMor3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cyclin/CDK positive transcription elongation factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent kinase 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gadus morhua Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference gadMor3.0 Primary Assembly

    Genomic

    1. NC_044049.1 Reference gadMor3.0 Primary Assembly

      Range
      12918797..12939890
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030350201.1 → XP_030206061.1  cyclin-dependent kinase 12 isoform X1

      UniProtKB/TrEMBL
      A0A8C4YT07
      Conserved Domains (1) summary
      cd07864
      Location:745 → 1046
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    2. XM_030350207.1 → XP_030206067.1  cyclin-dependent kinase 12 isoform X2

      UniProtKB/TrEMBL
      A0A8C4YT07, A0A8C5A3D4
      Related
      ENSGMOP00000025589.1, ENSGMOT00000068317.1
      Conserved Domains (1) summary
      cd07864
      Location:745 → 1046
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12
    Nucleotide Protein
    Heading Accession and Version

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