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    PLCB3 phospholipase C beta 3 [ Microcaecilia unicolor ]

    Gene ID: 115479646, updated on 17-Mar-2024

    Summary

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    Gene symbol
    PLCB3
    Gene description
    phospholipase C beta 3
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Microcaecilia unicolor
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Gymnophiona; Siphonopidae; Microcaecilia
    Orthologs
    human mouse all
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    Genomic context

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    See PLCB3 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    100 current aMicUni1.1 (GCF_901765095.1) 11 NC_044041.1 (112838382..112918664, complement)

    Chromosome 11 - NC_044041.1Genomic Context describing neighboring genes Neighboring gene glyoxal reductase-like Neighboring gene sodium/calcium exchanger 1-like Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14B Neighboring gene FKBP prolyl isomerase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_044041.1 Chromosome 11 Reference aMicUni1.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multi-tissue transcriptomes of caecilian amphibians highlight incomplete knowledge of vertebrate gene families. Torres-Sánchez M, et al. DNA Res, 2019 Feb 1. PMID 30351380, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Microcaecilia unicolor Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference aMicUni1.1 Primary Assembly

    Genomic

    1. NC_044041.1 Reference aMicUni1.1 Primary Assembly

      Range
      112838382..112918664 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030217704.1 → XP_030073564.1  LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

      UniProtKB/TrEMBL
      A0A6P7ZD72
      Conserved Domains (7) summary
      cd00275
      Location:713 → 829
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08591
      Location:316 → 679
      PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
      cd13361
      Location:22 → 149
      PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
      pfam15921
      Location:843 → 1063
      CCDC158; Coiled-coil domain-containing protein 158
      cd15898
      Location:154 → 183
      EFh_PI-PLC; EF-hand motif [structural motif]
      cl28895
      Location:154 → 304
      EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
      pfam08703
      Location:1018 → 1184
      PLC-beta_C; PLC-beta C terminal
    Nucleotide Protein
    Heading Accession and Version

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