U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    RGM1 Rgm1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855220, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RGM1
    Official Full Name
    Rgm1p
    Primary source
    SGD:S000004794
    Locus tag
    YMR182C
    See related
    AllianceGenome:SGD:S000004794; FungiDB:YMR182C; VEuPathDB:YMR182C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in positive regulation of transcription by RNA polymerase II. Located in chromatin; cytosol; and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RGM1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (624532..625167, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene polynucleotide 5'-phosphatase Neighboring gene uncharacterized protein Neighboring gene Min3p Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The yeast putative transcriptional repressor RGM1 is a proline-rich zinc finger protein. Estruch F. Nucleic Acids Res, 1991 Sep 25. PMID 1923755, Free PMC Article
    2. Structural and functional organization of RNA regulons in the post-transcriptional regulatory network of yeast. Joshi A, et al. Nucleic Acids Res, 2011 Nov. PMID 21840901, Free PMC Article
    3. Identifying transcription factor functions and targets by phenotypic activation. Chua G, et al. Proc Natl Acad Sci U S A, 2006 Aug 8. PMID 16880382, Free PMC Article
    4. Environment-responsive transcription factors bind subtelomeric elements and regulate gene silencing. Smith JJ, et al. Mol Syst Biol, 2011 Jan 4. PMID 21206489, Free PMC Article
    5. A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions. Sameith K, et al. BMC Biol, 2015 Dec 23. PMID 26700642, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Rgm1p
    NP_013907.1
    • Putative zinc finger DNA binding transcription factor; contains two N-terminal C2H2 zinc fingers and C-terminal proline rich domain; overproduction impairs cell growth and induces expression of genes involved in monosaccharide catabolism and aldehyde metabolism; regulates expression of of Y' telomeric elements and subtelomeric COS genes; relocalizes to the cytosol in response to hypoxia; RGM1 has a paralog, USV1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      624532..625167 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182688.1 → NP_013907.1  TPA: Rgm1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013907.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W005, Q00453
      UniProtKB/TrEMBL
      A6ZMP2, B3LM68, C7GTR9, G2WKN6, N1P0G4
      Conserved Domains (3) summary
      sd00017
      Location:21 → 44
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:19 → 44
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:36 → 61
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q00453.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools