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    tlr18 toll-like receptor 18 [ Betta splendens (Siamese fighting fish) ]

    Gene ID: 114843048, updated on 22-May-2024

    Summary

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    Gene symbol
    tlr18
    Gene description
    toll-like receptor 18
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Betta splendens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Anabantaria; Anabantiformes; Anabantoidei; Osphronemidae; Betta
    Orthologs
    zebrafish all
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    Genomic context

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    See tlr18 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_04 current fBetSpl5.4 (GCF_900634795.4) 16 NC_040896.2 (6454409..6460954, complement)
    101 previous assembly fBetSpl5.3 (GCF_900634795.3) 16 NC_040896.1 (6598922..6605467, complement)

    Chromosome 16 - NC_040896.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129603210 Neighboring gene S100 calcium binding protein A1 Neighboring gene uncharacterized LOC114842504 Neighboring gene leucine rich repeat and Ig domain containing 4b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of heart contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in toll-like receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    toll-like receptor 18
    Names
    toll-like receptor 2 type-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_900634795.4-RS_2023_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fBetSpl5.4 Primary Assembly

    Genomic

    1. NC_040896.2 Reference fBetSpl5.4 Primary Assembly

      Range
      6454409..6460954 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029129245.2 → XP_028985078.1  toll-like receptor 18

      UniProtKB/TrEMBL
      A0A6P7KR94
      Conserved Domains (7) summary
      smart00255
      Location:663 → 802
      TIR; Toll - interleukin 1 - resistance
      PLN00113
      Location:58 → 551
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      cd05025
      Location:919 → 1009
      S-100A1; S-100A1 domain found in proteins similar to S100A1. S100A1 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, to which this ...
      sd00031
      Location:60 → 83
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:372 → 399
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:83 → 141
      LRR_8; Leucine rich repeat
      cl29113
      Location:58 → 176
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    Nucleotide Protein
    Heading Accession and Version

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