IL4 interleukin 4 [Papio anubis (olive baboon)] - Gene

Summary

Gene symbol: IL4
Gene description: interleukin 4
See related: Ensembl:ENSPANG00000004677
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Papio anubis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Papio
Also known as: IL-4
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
104	current	Panubis1.0 (GCF_008728515.1)	5	NC_044980.1 (125436445..125444801)
103	previous assembly	Panu_3.0 (GCF_000264685.3)	6	NC_018157.2 (127015244..127023600)

Chromosome 5 - NC_044980.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

GDB:456299 (e-PCR)
- UniSTS:157483

GDB:207332 (e-PCR)
- UniSTS:156119

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed
enables growth factor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables interleukin-4 receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in B cell costimulation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in T-helper 2 cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in activation of Janus kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in extrinsic apoptotic signaling pathway in absence of ligand	IEA Inferred from Electronic Annotation more info	PubMed
involved_in innate immune response in mucosa	IEA Inferred from Electronic Annotation more info	PubMed
involved_in microglial cell activation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in myeloid dendritic cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of T-helper 17 cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of acute inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of chronic inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of complement-dependent cytotoxicity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of endothelial cell apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of epithelial cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of extrinsic apoptotic signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of macrophage activation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of MHC class II biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of T cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of amyloid-beta clearance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of defense response to virus by host	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of eosinophil chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of interleukin-10 production	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of interleukin-13 production	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of isotype switching to IgE isotypes	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of isotype switching to IgG isotypes	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of macroautophagy	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of mast cell degranulation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of mononuclear cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of myoblast fusion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of receptor-mediated endocytosis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of tyrosine phosphorylation of STAT protein	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: interleukin-4

Names: B-cell stimulatory factor 1; BSF-1; lymphocyte stimulatory factor 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.