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    CASP3 caspase 3 [ Ornithorhynchus anatinus (platypus) ]

    Gene ID: 100087105, updated on 30-Apr-2024

    Summary

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    Gene symbol
    CASP3
    Gene description
    caspase 3
    See related
    Ensembl:ENSOANG00000039253
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ornithorhynchus anatinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
    Orthologs
    human mouse all
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    Genomic context

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    See CASP3 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    105 current mOrnAna1.pri.v4 (GCF_004115215.2) 12 NC_041739.1 (1665110..1686949)

    Chromosome 12 - NC_041739.1Genomic Context describing neighboring genes Neighboring gene centromere protein U Neighboring gene primase and DNA directed polymerase Neighboring gene uncharacterized LOC114815504 Neighboring gene interferon regulatory factor 2 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_041739.1 Chromosome 12 Reference mOrnAna1.pri.v4 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity involved in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in erythrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in keratinocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    caspase-3
    Names
    caspase 3, apoptosis-related cysteine peptidase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mOrnAna1.pri.v4 Primary Assembly

    Genomic

    1. NC_041739.1 Reference mOrnAna1.pri.v4 Primary Assembly

      Range
      1665110..1686949
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029076645.2 → XP_028932478.1  caspase-3

      UniProtKB/TrEMBL
      A0A6I8NMY8
      Related
      ENSOANP00000042530.1
      Conserved Domains (1) summary
      cd00032
      Location:44 → 284
      CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

    2. XM_029076646.2 → XP_028932479.1  caspase-3

      UniProtKB/TrEMBL
      A0A6I8NMY8
      Conserved Domains (1) summary
      cd00032
      Location:44 → 284
      CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...
    Nucleotide Protein
    Heading Accession and Version

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