U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    Mdfi MyoD family inhibitor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501097, updated on 14-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Mdfiprovided by RGD
    Official Full Name
    MyoD family inhibitorprovided by RGD
    Primary source
    RGD:1560271
    See related
    EnsemblRapid:ENSRNOG00000014987 AllianceGenome:RGD:1560271
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560271
    Summary
    Predicted to enable DNA-binding transcription factor binding activity and identical protein binding activity. Predicted to be involved in dorsal/ventral axis specification; negative regulation of transcription by RNA polymerase II; and regulation of signal transduction. Predicted to act upstream of or within embryonic skeletal system morphogenesis and trophoblast giant cell differentiation. Predicted to be active in nucleus. Orthologous to human MDFI (MyoD family inhibitor). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 18.3), Kidney (RPKM 13.4) and 8 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Mdfi in Genome Data Viewer
    Location:
    9q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (20654359..20672768)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (13156806..13175218)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (15166118..15184469)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102554116 Neighboring gene forkhead box P4 Neighboring gene uncharacterized LOC134480340 Neighboring gene transcription factor EB Neighboring gene uncharacterized LOC102554309 Neighboring gene progastricsin

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in dorsal/ventral axis specification ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within embryonic skeletal system morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of JNK cascade ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within trophoblast giant cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    myoD family inhibitor

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109301.2 → NP_001102771.1  myoD family inhibitor

      See identical proteins and their annotated locations for NP_001102771.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A8I6GLH7, A6JIH8, B0BN88, F7EL63
      Related
      ENSRNOP00000020432.3, ENSRNOT00000020432.6
      Conserved Domains (1) summary
      pfam15316
      Location:88 → 247
      MDFI; MyoD family inhibitor

    2. NM_001432172.1 → NP_001419101.1  myoD family inhibitor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A6JIH8, B0BN88, F7EL63

    3. NM_001432173.1 → NP_001419102.1  myoD family inhibitor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A6JIH8, B0BN88, F7EL63

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      20654359..20672768
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244476.5 → XP_006244538.1  myoD family inhibitor isoform X1

      Conserved Domains (1) summary
      pfam15316
      Location:88 → 247
      MDFI; MyoD family inhibitor

    2. XM_006244475.5 → XP_006244537.1  myoD family inhibitor isoform X1

      Conserved Domains (1) summary
      pfam15316
      Location:88 → 247
      MDFI; MyoD family inhibitor
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools