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    PTP4A2 protein tyrosine phosphatase 4A2 [ Bos taurus (domestic cattle) ]

    Gene ID: 614435, updated on 4-Oct-2024

    Summary

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    Official Symbol
    PTP4A2provided by VGNC
    Official Full Name
    protein tyrosine phosphatase 4A2provided by VGNC
    Primary source
    VGNC:VGNC:33524
    See related
    BGD:BT28098; Ensembl:ENSBTAG00000039121
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    PTP4A3
    Orthologs
    human mouse all
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    Genomic context

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    See PTP4A2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (121791275..121819537)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene microRNA 2887-1 Neighboring gene uncharacterized LOC112443213 Neighboring gene refilin-B-like Neighboring gene tubulin alpha-1C chain Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene large ribosomal subunit protein uL13-like Neighboring gene SPOC domain containing 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC159683, MGC179416

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein tyrosine phosphatase type IVA 3; protein tyrosine phosphatase type IVA 2
    Names
    protein tyrosine phosphatase type IVA, member 2
    protein-tyrosine phosphatase 4a3
    NP_001098468.1
    XP_005203059.1
    XP_024833355.1
    XP_024833362.1
    XP_059732486.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104998.1 → NP_001098468.1  protein tyrosine phosphatase type IVA 3

      See identical proteins and their annotated locations for NP_001098468.1

      Status: PROVISIONAL

      Source sequence(s)
      BC147865
      UniProtKB/TrEMBL
      A6QL75, F1MEE0
      Related
      ENSBTAP00000048125.3, ENSBTAT00000054758.4
      Conserved Domains (1) summary
      cd18536
      Location:1 → 155
      PTP-IVa2; protein tyrosine phosphatase type IVA 2

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      121791275..121819537
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005203002.5 → XP_005203059.1  protein tyrosine phosphatase type IVA 2 isoform X1

      See identical proteins and their annotated locations for XP_005203059.1

      UniProtKB/TrEMBL
      A6QL75, F1MEE0
      Conserved Domains (1) summary
      cd18536
      Location:1 → 155
      PTP-IVa2; protein tyrosine phosphatase type IVA 2

    2. XM_024977594.2 → XP_024833362.1  protein tyrosine phosphatase type IVA 2 isoform X2

      Conserved Domains (1) summary
      cl21483
      Location:8 → 146
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

    3. XM_059876503.1 → XP_059732486.1  protein tyrosine phosphatase type IVA 2 isoform X1

      UniProtKB/TrEMBL
      A6QL75, F1MEE0

    4. XM_024977587.2 → XP_024833355.1  protein tyrosine phosphatase type IVA 2 isoform X1

      UniProtKB/TrEMBL
      A6QL75, F1MEE0
      Conserved Domains (1) summary
      cd18536
      Location:1 → 155
      PTP-IVa2; protein tyrosine phosphatase type IVA 2
    Nucleotide Protein Strain
    Heading Accession and Version

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