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    ppm1aa protein phosphatase, Mg2+/Mn2+ dependent, 1Aa [ Xiphophorus couchianus (Monterrey platyfish) ]

    Gene ID: 114133823, updated on 15-Mar-2024

    Summary

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    Gene symbol
    ppm1aa
    Gene description
    protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xiphophorus couchianus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
    Also known as
    ppm1a
    Orthologs
    human zebrafish all
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    Genomic context

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    See ppm1aa in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    101 current X_couchianus-1.0 (GCF_001444195.1) 19 NC_040246.1 (18828017..18884775)

    Chromosome 19 - NC_040246.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 9 Neighboring gene pecanex 4 Neighboring gene dehydrogenase/reductase (SDR family) member 7 Neighboring gene uncharacterized LOC114133825 Neighboring gene uncharacterized LOC114133824 Neighboring gene SIX homeobox 6a Neighboring gene SIX homeobox 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_040246.1 Chromosome 19 Reference X_couchianus-1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables manganese ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase 1A
    Names
    protein phosphatase, Mg2+/Mn2+ dependent 1A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xiphophorus couchianus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference X_couchianus-1.0 Primary Assembly

    Genomic

    1. NC_040246.1 Reference X_couchianus-1.0 Primary Assembly

      Range
      18828017..18884775
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027999917.1 → XP_027855718.1  protein phosphatase 1A isoform X2

      UniProtKB/TrEMBL
      A0A3B5LKY7
      Conserved Domains (2) summary
      cd00143
      Location:23 → 292
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:286 → 362
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    2. XM_027999915.1 → XP_027855716.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A3B5LKY7
      Conserved Domains (2) summary
      cd00143
      Location:23 → 292
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:286 → 362
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    3. XM_027999920.1 → XP_027855721.1  protein phosphatase 1A isoform X4

      UniProtKB/TrEMBL
      A0A3B5LKY7
      Conserved Domains (2) summary
      cd00143
      Location:23 → 292
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:286 → 362
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    4. XM_027999918.1 → XP_027855719.1  protein phosphatase 1A isoform X3

      UniProtKB/TrEMBL
      A0A3B5LKY7
      Conserved Domains (2) summary
      cd00143
      Location:23 → 292
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:286 → 362
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    5. XM_027999916.1 → XP_027855717.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A3B5LKY7
      Conserved Domains (2) summary
      cd00143
      Location:23 → 292
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:286 → 362
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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