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    Hspg2 heparan sulfate proteoglycan 2 [ Urocitellus parryii (Arctic ground squirrel) ]

    Gene ID: 113193175, updated on 15-Mar-2024

    Summary

    Gene symbol
    Hspg2
    Gene description
    heparan sulfate proteoglycan 2
    See related
    Ensembl:ENSUPAG00010020689
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Urocitellus parryii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Urocitellus
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Hspg2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    103
    Annotation release Status Assembly Chr Location
    100 current ASM342692v1 (GCF_003426925.1) Unplaced Scaffold NW_020540182.1 (223761..313162, complement)

    NW_020540182.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 48 Neighboring gene low density lipoprotein receptor class A domain containing 2 Neighboring gene uncharacterized LOC113193224 Neighboring gene proproteinase E

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NW_020540182 Unplaced Scaffold Reference ASM342692v1

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables cell adhesion molecule binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    basement membrane-specific heparan sulfate proteoglycan core protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Urocitellus parryii Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM342692v1

    Genomic

    1. NW_020540182.1 Reference ASM342692v1

      Range
      223761..313162 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_026403561.1XP_026259346.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X2

      Conserved Domains (19) summary
      cd05743
      Location:437514
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:19492034
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:301332
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:608732
      LamB; Laminin B domain
      smart00409
      Location:33973471
      IG; Immunoglobulin
      smart00410
      Location:22352312
      IG_like; Immunoglobulin like
      cd00054
      Location:40344063
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11811230
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:43854544
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:344375
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:37523834
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12981345
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:42904320
      EGF; EGF-like domain
      pfam00052
      Location:10131147
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:28092879
      Ig_3; Immunoglobulin domain
      cd00096
      Location:27322791
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:35933659
      Ig; Immunoglobulin domain
      cl28434
      Location:31993285
      I-set; Immunoglobulin I-set domain
    2. XM_026403567.1XP_026259352.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X8

      Conserved Domains (19) summary
      cd05743
      Location:437514
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:19502035
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:301332
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:608732
      LamB; Laminin B domain
      smart00409
      Location:24312505
      IG; Immunoglobulin
      smart00410
      Location:33003374
      IG_like; Immunoglobulin like
      cd00054
      Location:39373966
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11811230
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:42884447
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:344375
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:36553737
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12981345
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:41934223
      EGF; EGF-like domain
      pfam00052
      Location:10131147
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:28102880
      Ig_3; Immunoglobulin domain
      cd00096
      Location:27332792
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:34963562
      Ig; Immunoglobulin domain
      cl28434
      Location:31023188
      I-set; Immunoglobulin I-set domain
    3. XM_026403565.1XP_026259350.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X6

      Conserved Domains (19) summary
      cd05743
      Location:437514
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:19502035
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:301332
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:608732
      LamB; Laminin B domain
      smart00409
      Location:33983472
      IG; Immunoglobulin
      smart00410
      Location:22362313
      IG_like; Immunoglobulin like
      cd00054
      Location:40294058
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11811230
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:43804538
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:344375
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:37533835
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12981345
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:42854315
      EGF; EGF-like domain
      pfam00052
      Location:10131147
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:28102880
      Ig_3; Immunoglobulin domain
      cd00096
      Location:27332792
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:35943660
      Ig; Immunoglobulin domain
      cl28434
      Location:32003286
      I-set; Immunoglobulin I-set domain
    4. XM_026403563.1XP_026259348.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X4

      Conserved Domains (19) summary
      cd05743
      Location:437514
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:19502035
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:301332
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:608732
      LamB; Laminin B domain
      smart00409
      Location:33983472
      IG; Immunoglobulin
      smart00410
      Location:22362313
      IG_like; Immunoglobulin like
      cd00054
      Location:40294058
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11811230
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:43804539
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:344375
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:37533835
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12981345
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:42854315
      EGF; EGF-like domain
      pfam00052
      Location:10131147
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:28102880
      Ig_3; Immunoglobulin domain
      cd00096
      Location:27332792
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:35943660
      Ig; Immunoglobulin domain
      cl28434
      Location:32003286
      I-set; Immunoglobulin I-set domain
    5. XM_026403562.1XP_026259347.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X3

      Conserved Domains (19) summary
      cd05743
      Location:437514
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:19502035
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:301332
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:608732
      LamB; Laminin B domain
      smart00409
      Location:33983472
      IG; Immunoglobulin
      smart00410
      Location:22362313
      IG_like; Immunoglobulin like
      cd00054
      Location:40354064
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11811230
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:43864544
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:344375
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:37533835
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12981345
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:42914321
      EGF; EGF-like domain
      pfam00052
      Location:10131147
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:28102880
      Ig_3; Immunoglobulin domain
      cd00096
      Location:27332792
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:35943660
      Ig; Immunoglobulin domain
      cl28434
      Location:32003286
      I-set; Immunoglobulin I-set domain
    6. XM_026403560.1XP_026259345.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X1

      Conserved Domains (19) summary
      cd05743
      Location:437514
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:19502035
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:301332
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:608732
      LamB; Laminin B domain
      smart00409
      Location:33983472
      IG; Immunoglobulin
      smart00410
      Location:22362313
      IG_like; Immunoglobulin like
      cd00054
      Location:40354064
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11811230
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:43864545
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:344375
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:37533835
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12981345
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:42914321
      EGF; EGF-like domain
      pfam00052
      Location:10131147
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:28102880
      Ig_3; Immunoglobulin domain
      cd00096
      Location:27332792
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:35943660
      Ig; Immunoglobulin domain
      cl28434
      Location:32003286
      I-set; Immunoglobulin I-set domain
    7. XM_026403572.1XP_026259357.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X12

      Conserved Domains (19) summary
      cd05743
      Location:420497
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:17691854
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:284315
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:13901515
      LamB; Laminin B domain
      smart00409
      Location:27322809
      IG; Immunoglobulin
      smart00410
      Location:32173291
      IG_like; Immunoglobulin like
      cd00054
      Location:38483877
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11571206
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:41994357
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:327358
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:35723654
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12741321
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:41044134
      EGF; EGF-like domain
      pfam00052
      Location:9891123
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:26292699
      Ig_3; Immunoglobulin domain
      cd00096
      Location:25522611
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:34133479
      Ig; Immunoglobulin domain
      cl28434
      Location:30193105
      I-set; Immunoglobulin I-set domain
    8. XM_026403566.1XP_026259351.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X7

      Conserved Domains (19) summary
      cd05743
      Location:420497
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:19332018
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:284315
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:591715
      LamB; Laminin B domain
      smart00409
      Location:33813455
      IG; Immunoglobulin
      smart00410
      Location:24142488
      IG_like; Immunoglobulin like
      cd00054
      Location:40184047
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11641213
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:43694528
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:327358
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:37363818
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12811328
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:42744304
      EGF; EGF-like domain
      pfam00052
      Location:9961130
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:27932863
      Ig_3; Immunoglobulin domain
      cd00096
      Location:27162775
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:35773643
      Ig; Immunoglobulin domain
      cl28434
      Location:31833269
      I-set; Immunoglobulin I-set domain
    9. XM_026403564.1XP_026259349.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X5

      Conserved Domains (19) summary
      cd05743
      Location:437514
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:19432028
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:301332
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:608732
      LamB; Laminin B domain
      smart00409
      Location:22292306
      IG; Immunoglobulin
      smart00410
      Location:33913465
      IG_like; Immunoglobulin like
      cd00054
      Location:40284057
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11741223
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:43794538
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:344375
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:37463828
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12911338
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:42844314
      EGF; EGF-like domain
      pfam00052
      Location:10061140
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:28032873
      Ig_3; Immunoglobulin domain
      cd00096
      Location:27262785
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:35873653
      Ig; Immunoglobulin domain
      cl28434
      Location:31933279
      I-set; Immunoglobulin I-set domain
    10. XM_026403568.1XP_026259353.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X9

      Conserved Domains (19) summary
      cd05743
      Location:437514
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:17941879
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:301332
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:14141539
      LamB; Laminin B domain
      smart00409
      Location:32423316
      IG; Immunoglobulin
      smart00410
      Location:22752349
      IG_like; Immunoglobulin like
      cd00054
      Location:38793908
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11811230
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:42304389
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:344375
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:35973679
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12981345
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:41354165
      EGF; EGF-like domain
      pfam00052
      Location:10131147
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:26542724
      Ig_3; Immunoglobulin domain
      cd00096
      Location:25772636
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:34383504
      Ig; Immunoglobulin domain
      cl28434
      Location:30443130
      I-set; Immunoglobulin I-set domain
    11. XM_026403570.1XP_026259355.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X11

      Conserved Domains (19) summary
      cd05743
      Location:420497
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:17691854
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:284315
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:13901515
      LamB; Laminin B domain
      smart00409
      Location:27322809
      IG; Immunoglobulin
      smart00410
      Location:32173291
      IG_like; Immunoglobulin like
      cd00054
      Location:38543883
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11571206
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:42054364
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:327358
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:35723654
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12741321
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:41104140
      EGF; EGF-like domain
      pfam00052
      Location:9891123
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:26292699
      Ig_3; Immunoglobulin domain
      cd00096
      Location:25522611
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:34133479
      Ig; Immunoglobulin domain
      cl28434
      Location:30193105
      I-set; Immunoglobulin I-set domain
    12. XM_026403573.1XP_026259358.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X13

      Related
      ENSUPAT00010029885.1
      Conserved Domains (19) summary
      cd05743
      Location:420497
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:17701855
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:284315
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:13901515
      LamB; Laminin B domain
      smart00409
      Location:27332810
      IG; Immunoglobulin
      smart00410
      Location:32183292
      IG_like; Immunoglobulin like
      cd00054
      Location:38493878
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11571206
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:42004359
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:327358
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:35733655
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12741321
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:41054135
      EGF; EGF-like domain
      pfam00052
      Location:9891123
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:26302700
      Ig_3; Immunoglobulin domain
      cd00096
      Location:25532612
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:34143480
      Ig; Immunoglobulin domain
      cl28434
      Location:30203106
      I-set; Immunoglobulin I-set domain
    13. XM_026403569.1XP_026259354.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X10

      Conserved Domains (19) summary
      cd05743
      Location:420497
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
      cd05754
      Location:17701855
      Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
      smart00192
      Location:284315
      LDLa; Low-density lipoprotein receptor domain class A
      smart00281
      Location:13901515
      LamB; Laminin B domain
      smart00409
      Location:27332810
      IG; Immunoglobulin
      smart00410
      Location:32183292
      IG_like; Immunoglobulin like
      cd00054
      Location:38553884
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:11571206
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:42064365
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:327358
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam07679
      Location:35733655
      I-set; Immunoglobulin I-set domain
      pfam00053
      Location:12741321
      Laminin_EGF; Laminin EGF domain
      pfam00008
      Location:41114141
      EGF; EGF-like domain
      pfam00052
      Location:9891123
      Laminin_B; Laminin B (Domain IV)
      pfam13927
      Location:26302700
      Ig_3; Immunoglobulin domain
      cd00096
      Location:25532612
      Ig; Immunoglobulin domain
      cl02507
      Location:80194
      SEA; SEA domain
      cl11960
      Location:34143480
      Ig; Immunoglobulin domain
      cl28434
      Location:30203106
      I-set; Immunoglobulin I-set domain