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    nr1i2 nuclear receptor subfamily 1, group I, member 2 [ Oncorhynchus mykiss (rainbow trout) ]

    Gene ID: 100136707, updated on 8-Mar-2024

    Summary

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    Gene symbol
    nr1i2
    Gene description
    nuclear receptor subfamily 1, group I, member 2
    See related
    Ensembl:ENSOMYG00000014861
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oncorhynchus mykiss
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
    Orthologs
    human zebrafish all
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    Genomic context

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    See nr1i2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    101 current USDA_OmykA_1.1 (GCF_013265735.2) 3 NC_048567.1 (68125603..68147765, complement)
    100 previous assembly Omyk_1.0 (GCF_002163495.1) 3 NC_035079.1 (70988863..71004729, complement)

    Chromosome 3 - NC_048567.1Genomic Context describing neighboring genes Neighboring gene probable G-protein coupled receptor 156 Neighboring gene glycogen synthase kinase-3 beta Neighboring gene cell surface glycoprotein CD200 receptor 1-A Neighboring gene uncharacterized si:ch211-214p13.7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interactions of pharmaceuticals and other xenobiotics on hepatic pregnane X receptor and cytochrome P450 3A signaling pathway in rainbow trout (Oncorhynchus mykiss). Wassmur B, et al. Aquat Toxicol, 2010 Oct 1. PMID 20719396

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear receptor subfamily 1 group I member 2
    Names
    pregnane X receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001124672.1 → NP_001118144.1  nuclear receptor subfamily 1 group I member 2

      See identical proteins and their annotated locations for NP_001118144.1

      Status: PROVISIONAL

      Source sequence(s)
      EF517132
      UniProtKB/TrEMBL
      A0A8C7Q381, A5A0Y5
      Related
      ENSOMYP00000031732.2, ENSOMYT00000034595.2
      Conserved Domains (2) summary
      cd06934
      Location:126 → 450
      NR_LBD_PXR_like; The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor
      cd07162
      Location:30 → 116
      NR_DBD_PXR; DNA-binding domain of pregnane X receptor (PXRs) is composed of two C4-type zinc fingers

    RefSeqs of Annotated Genomes: Oncorhynchus mykiss Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference USDA_OmykA_1.1 Primary Assembly

    Genomic

    1. NC_048567.1 Reference USDA_OmykA_1.1 Primary Assembly

      Range
      68125603..68147765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036963368.1 → XP_036819263.1  nuclear receptor subfamily 1 group I member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C7Q381, A0A8C7Q4J4
      Conserved Domains (2) summary
      cd06934
      Location:126 → 450
      NR_LBD_PXR_like; The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor
      cd07162
      Location:30 → 116
      NR_DBD_PXR; DNA-binding domain of pregnane X receptor (PXRs) is composed of two C4-type zinc fingers

    2. XM_036963363.1 → XP_036819258.1  nuclear receptor subfamily 1 group I member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C7Q381, A0A8C7Q4J4
      Related
      ENSOMYP00000031733.2, ENSOMYT00000034598.2
      Conserved Domains (2) summary
      cd06934
      Location:126 → 450
      NR_LBD_PXR_like; The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor
      cd07162
      Location:30 → 116
      NR_DBD_PXR; DNA-binding domain of pregnane X receptor (PXRs) is composed of two C4-type zinc fingers
    Nucleotide Protein
    Heading Accession and Version

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