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    EPHA1 EPH receptor A1 [ Canis lupus dingo (dingo) ]

    Gene ID: 112650880, updated on 10-Oct-2024

    Summary

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    Gene symbol
    EPHA1
    Gene description
    EPH receptor A1
    See related
    Ensembl:ENSCAFG00020020716
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus dingo (sub-species: dingo)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See EPHA1 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    102 current ASM325472v2 (GCF_003254725.2) 16 NC_064258.1 (6204544..6220804)
    101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 16 Unlocalized Scaffold NW_023365166.1 (6001283..6017520)

    Chromosome 16 - NC_064258.1Genomic Context describing neighboring genes Neighboring gene taste receptor type 2 member 143-like Neighboring gene uncharacterized LOC112651043 Neighboring gene zyxin Neighboring gene uncharacterized LOC118350993

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane-ephrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ephrin type-A receptor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM325472v2

    Genomic

    1. NC_064258.1 Reference ASM325472v2

      Range
      6204544..6220804
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_049094722.1 → XP_048950679.1  ephrin type-A receptor 1 isoform X1

    2. XM_025433753.3 → XP_025289538.1  ephrin type-A receptor 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0Q3H9, A0A8C0RI01, A0A8P0N6F4
      Conserved Domains (6) summary
      cd09542
      Location:912 → 974
      SAM_EPH-A1; SAM domain of EPH-A1 subfamily of tyrosine kinase receptors
      cd10479
      Location:27 → 203
      EphR_LBD_A1; Ligand Binding Domain of Ephrin type-A Receptor 1
      cd00063
      Location:453 → 535
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:334 → 431
      fn3; Fibronectin type III domain
      pfam14575
      Location:548 → 621
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl21453
      Location:619 → 884
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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