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    SPTLC1 serine palmitoyltransferase long chain base subunit 1 [ Alligator sinensis (Chinese alligator) ]

    Gene ID: 102387546, updated on 10-Mar-2024

    Summary

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    Gene symbol
    SPTLC1
    Gene description
    serine palmitoyltransferase long chain base subunit 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Alligator sinensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
    Orthologs
    human mouse all
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    Genomic context

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    See SPTLC1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    102 current ASM45574v1 (GCF_000455745.1) Unplaced Scaffold NW_005842652.1 (646037..700145)

    NW_005842652.1Genomic Context describing neighboring genes Neighboring gene CDC42 small effector 2 Neighboring gene uncharacterized LOC102387379

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_005842652 Unplaced Scaffold Reference ASM45574v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine C-palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingosine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine palmitoyltransferase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Alligator sinensis Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM45574v1 Primary Assembly

    Genomic

    1. NW_005842652.1 Reference ASM45574v1 Primary Assembly

      Range
      646037..700145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006033677.3 → XP_006033739.1  serine palmitoyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A1U7S2T2
      Conserved Domains (2) summary
      COG0156
      Location:94 → 468
      BioF; 7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]
      cl18945
      Location:25 → 473
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

    2. XM_025215566.1 → XP_025071351.1  serine palmitoyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q0HHC4
      Conserved Domains (1) summary
      cl18945
      Location:25 → 188
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

    3. XM_025215567.1 → XP_025071352.1  serine palmitoyltransferase 1 isoform X3

      UniProtKB/TrEMBL
      A0A3Q0HI60
      Conserved Domains (1) summary
      cl18945
      Location:25 → 142
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
    Nucleotide Protein
    Heading Accession and Version

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