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    HRH2 histamine receptor H2 [ Canis lupus familiaris (dog) ]

    Gene ID: 403812, updated on 17-Aug-2024

    Summary

    Official Symbol
    HRH2provided by VGNC
    Official Full Name
    histamine receptor H2provided by VGNC
    Primary source
    VGNC:VGNC:41787
    See related
    Ensembl:ENSCAFG00845000310
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    H2R; HH2R
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See HRH2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (37699668..37772370, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (37330979..37332058, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (38272467..38273546, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (37574680..37575759, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (37762745..37763824, complement)

    Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene THO complex subunit 3 Neighboring gene complexin 2 Neighboring gene 40S ribosomal protein S11-like Neighboring gene uncharacterized LOC111095711 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General protein information

    Preferred Names
    histamine H2 receptor
    Names
    gastric receptor I
    histamine receptor subtype H2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195844.1NP_001182773.1  histamine H2 receptor

      See identical proteins and their annotated locations for NP_001182773.1

      Status: PROVISIONAL

      Source sequence(s)
      JAAUVH010000355
      UniProtKB/Swiss-Prot
      P17124
      UniProtKB/TrEMBL
      A0A8C0KGF2, A0A8C0T527, A0A8I3MAL7
      Conserved Domains (2) summary
      cd14964
      Location:2046
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:19299
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051808.1 Reference ROS_Cfam_1.0

      Range
      37699668..37772370 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038662231.1XP_038518159.1  histamine H2 receptor isoform X6

      UniProtKB/Swiss-Prot
      P17124
      UniProtKB/TrEMBL
      A0A8C0KGF2, A0A8C0T527, A0A8I3MAL7
      Related
      ENSCAFP00845000340.1, ENSCAFT00845000497.1
      Conserved Domains (2) summary
      cd14964
      Location:2046
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:19299
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    2. XM_038662225.1XP_038518153.1  histamine H2 receptor isoform X1

      Conserved Domains (2) summary
      PHA03247
      Location:392535
      PHA03247; large tegument protein UL36; Provisional
      cd15051
      Location:19299
      7tmA_Histamine_H2R; histamine subtype H2 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
    3. XM_038662226.1XP_038518154.1  histamine H2 receptor isoform X1

      Conserved Domains (2) summary
      PHA03247
      Location:392535
      PHA03247; large tegument protein UL36; Provisional
      cd15051
      Location:19299
      7tmA_Histamine_H2R; histamine subtype H2 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
    4. XM_038662228.1XP_038518156.1  histamine H2 receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0M1M9, A0A8I3MCA9, A0A8I3MF03, A0A8P0NI50
      Related
      ENSCAFP00845000347.1, ENSCAFT00845000506.1
      Conserved Domains (1) summary
      cd15051
      Location:19299
      7tmA_Histamine_H2R; histamine subtype H2 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
    5. XM_038662227.1XP_038518155.1  histamine H2 receptor isoform X2

      UniProtKB/TrEMBL
      A0A8C0M8J4, A0A8I3MCA9, A0A8I3MF06, A0A8P0NI50
      Related
      ENSCAFP00845000359.1, ENSCAFT00845000522.1
      Conserved Domains (1) summary
      cd15051
      Location:19299
      7tmA_Histamine_H2R; histamine subtype H2 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
    6. XM_038662230.1XP_038518158.1  histamine H2 receptor isoform X5

      UniProtKB/TrEMBL
      A0A8C0T527, A0A8I3MAL7
      Conserved Domains (2) summary
      cd14964
      Location:2046
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:19299
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    7. XM_038662229.1XP_038518157.1  histamine H2 receptor isoform X4

      UniProtKB/TrEMBL
      A0A8C0T527, A0A8I3MAL7
      Conserved Domains (2) summary
      cd14964
      Location:2046
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:19299
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RNA

    1. XR_005425096.1 RNA Sequence

    2. XR_005425097.1 RNA Sequence

    3. XR_005425098.1 RNA Sequence

    4. XR_005425099.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049264.1 Alternate UMICH_Zoey_3.1

      Range
      37574680..37575759 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

      Range
      37762745..37763824 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

      Range
      38272467..38273546 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      37330979..37332058 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)