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    nfkbie nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon [ Danio rerio (zebrafish) ]

    Gene ID: 790944, updated on 2-Nov-2024

    Summary

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    Official Symbol
    nfkbieprovided by ZNC
    Official Full Name
    nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilonprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061215-132
    See related
    Ensembl:ENSDARG00000068367 AllianceGenome:ZFIN:ZDB-GENE-061215-132
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:158276
    Summary
    Orthologous to human NFKBIE (NFKB inhibitor epsilon). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See nfkbie in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (51274296..51307815, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (51461164..51494683, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene heat shock protein 90, alpha (cytosolic), class B member 1 Neighboring gene solute carrier family 35 member B2 Neighboring gene transmembrane protein 151Ba Neighboring gene t-complex-associated-testis-expressed 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis. Di Giaimo R, et al. Cell Rep, 2018 Dec 18. PMID 30566853
    2. Silica nanoparticles trigger hepatic lipid-metabolism disorder in vivo and in vitro. Duan J, et al. Int J Nanomedicine, 2018. PMID 30519016, Free PMC Article
    3. A zebrafish model of granulin deficiency reveals essential roles in myeloid cell differentiation. Campbell CA, et al. Blood Adv, 2021 Feb 9. PMID 33560393, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    NF-kappa-B inhibitor epsilon

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080089.1 → NP_001073558.1  NF-kappa-B inhibitor epsilon

      See identical proteins and their annotated locations for NP_001073558.1

      Status: PROVISIONAL

      Source sequence(s)
      BC128831
      UniProtKB/TrEMBL
      A1A5V8
      Related
      ENSDARP00000089603.3, ENSDART00000098833.5
      Conserved Domains (3) summary
      cd00204
      Location:166 → 295
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:213 → 306
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:208 → 239
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      51274296..51307815 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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