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    HPGD 15-hydroxyprostaglandin dehydrogenase [ Sus scrofa (pig) ]

    Gene ID: 100156186, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HPGDprovided by VGNC
    Official Full Name
    15-hydroxyprostaglandin dehydrogenaseprovided by VGNC
    Primary source
    VGNC:VGNC:88961
    See related
    Ensembl:ENSSSCG00000009699
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in spleen (RPKM 34.5), liver (RPKM 22.5) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See HPGD in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (15718261..15773534)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (16909010..16921261)

    Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene glycine receptor alpha 3 Neighboring gene uncharacterized LOC110256873 Neighboring gene 40S ribosomal protein S26-like Neighboring gene E3 ubiquitin-protein ligase RNF168 pseudogene Neighboring gene centrosomal protein 44 Neighboring gene F-box protein 8 Neighboring gene uncharacterized LOC102163133

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
    2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    15-hydroxyprostaglandin dehydrogenase [NAD(+)]
    Names
    hydroxyprostaglandin dehydrogenase 15-(NAD)
    NP_001177177.1
    XP_020927633.1
    XP_020927634.1
    XP_020927635.1
    XP_020927636.1
    XP_020927637.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190248.1 → NP_001177177.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)]

      See identical proteins and their annotated locations for NP_001177177.1

      Status: PROVISIONAL

      Source sequence(s)
      AB529533
      UniProtKB/TrEMBL
      A0A4X1V850, A0A8D1WXZ3, D0G6X9, F6PT21
      Related
      ENSSSCP00000010358.3, ENSSSCT00000010634.4
      Conserved Domains (2) summary
      cd05323
      Location:6 → 254
      ADH_SDR_c_like; insect type alcohol dehydrogenase (ADH)-like, classical (c) SDRs
      pfam00106
      Location:6 → 199
      adh_short; short chain dehydrogenase

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

      Range
      15718261..15773534
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021071975.1 → XP_020927634.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X2

      UniProtKB/TrEMBL
      A0A4X1V860, A0A5G2R1D3
      Conserved Domains (1) summary
      cl25409
      Location:6 → 141
      SDR; Short-chain dehydrogenases/reductases (SDR)

    2. XM_021071977.1 → XP_020927636.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X2

      UniProtKB/TrEMBL
      A0A4X1V860, A0A5G2R1D3
      Conserved Domains (1) summary
      cl25409
      Location:6 → 141
      SDR; Short-chain dehydrogenases/reductases (SDR)

    3. XM_021071976.1 → XP_020927635.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X2

      UniProtKB/TrEMBL
      A0A4X1V860, A0A5G2R1D3
      Conserved Domains (1) summary
      cl25409
      Location:6 → 141
      SDR; Short-chain dehydrogenases/reductases (SDR)

    4. XM_021071978.1 → XP_020927637.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X3

      UniProtKB/TrEMBL
      A0A4X1V860, A0A5G2R1D3
      Related
      ENSSSCP00000070923.1, ENSSSCT00000086201.2
      Conserved Domains (1) summary
      cl25409
      Location:6 → 141
      SDR; Short-chain dehydrogenases/reductases (SDR)

    5. XM_021071974.1 → XP_020927633.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X1

      Conserved Domains (1) summary
      cl25409
      Location:21 → 169
      SDR; Short-chain dehydrogenases/reductases (SDR)

    RNA

    1. XR_002338278.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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