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    SRD5A1 steroid 5 alpha-reductase 1 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 743740, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SRD5A1provided by VGNC
    Official Full Name
    steroid 5 alpha-reductase 1provided by VGNC
    Primary source
    VGNC:VGNC:7155
    Locus tag
    CK820_G0036026
    See related
    Ensembl:ENSPTRG00000016716
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See SRD5A1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (7304604..7339918)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (7575066..7619172)

    Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugating enzyme E2 QL1 Neighboring gene uncharacterized LOC461710 Neighboring gene NOP2/Sun RNA methyltransferase 2 Neighboring gene uncharacterized LOC134810050 Neighboring gene uncharacterized LOC107974609

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in steroid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Names
    steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
    XP_001144570.1
    XP_016808418.3
    XP_016808419.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      7304604..7339918
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001144570.6 → XP_001144570.1  3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X1

      See identical proteins and their annotated locations for XP_001144570.1

      UniProtKB/TrEMBL
      A0A2J8KU41, A0A6D2W9I8, H2QQM0
      Related
      ENSPTRP00000028677.3
      Conserved Domains (1) summary
      pfam02544
      Location:110 → 259
      Steroid_dh; 3-oxo-5-alpha-steroid 4-dehydrogenase

    2. XM_016952929.3 → XP_016808418.3  3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X2

      UniProtKB/TrEMBL
      A0A2I3T4Q9

    3. XM_016952930.4 → XP_016808419.1  3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X3

    Nucleotide Protein
    Heading Accession and Version

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