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    EPN3 epsin 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 538660, updated on 4-Oct-2024

    Summary

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    Official Symbol
    EPN3provided by VGNC
    Official Full Name
    epsin 3provided by VGNC
    Primary source
    VGNC:VGNC:28548
    See related
    BGD:BT20366; Ensembl:ENSBTAG00000015893
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See EPN3 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (36181633..36192383, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene calcium voltage-gated channel subunit alpha1 G Neighboring gene uncharacterized LOC101902385 Neighboring gene spermatogenesis associated 20 Neighboring gene MYCBP associated protein Neighboring gene radical S-adenosyl methionine domain containing 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC137304

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables clathrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of clathrin vesicle coat IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    epsin-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046434.1 → NP_001039899.1  epsin-3

      See identical proteins and their annotated locations for NP_001039899.1

      Status: PROVISIONAL

      Source sequence(s)
      BC112775
      UniProtKB/TrEMBL
      Q2KI44
      Related
      ENSBTAP00000040887.4, ENSBTAT00000043309.5
      Conserved Domains (2) summary
      smart00726
      Location:201 → 220
      UIM; Ubiquitin-interacting motif
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      36181633..36192383 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015458784.3 → XP_015314270.2  epsin-3 isoform X2

      UniProtKB/TrEMBL
      F1N4F8
      Conserved Domains (3) summary
      smart00726
      Location:201 → 220
      UIM; Ubiquitin-interacting motif
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      cl26464
      Location:272 → 606
      Atrophin-1; Atrophin-1 family

    2. XM_015458782.3 → XP_015314268.2  epsin-3 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M4S2
      Related
      ENSBTAP00000063264.1, ENSBTAT00000075862.2
      Conserved Domains (3) summary
      smart00726
      Location:201 → 220
      UIM; Ubiquitin-interacting motif
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      cl26464
      Location:299 → 633
      Atrophin-1; Atrophin-1 family

    3. XM_015458783.3 → XP_015314269.2  epsin-3 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M4S2
      Conserved Domains (3) summary
      smart00726
      Location:201 → 220
      UIM; Ubiquitin-interacting motif
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      cl26464
      Location:299 → 633
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein Strain
    Heading Accession and Version

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