pstpip1a proline-serine-threonine phosphatase interacting protein 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pstpip1aprovided by ZNC
Official Full Name: proline-serine-threonine phosphatase interacting protein 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050419-251
See related: Ensembl:ENSDARG00000060860 AllianceGenome:ZFIN:ZDB-GENE-050419-251
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkey-24l11.5
Summary: Predicted to enable actin filament binding activity. Predicted to be involved in actin filament polymerization. Predicted to be active in actin filament; cytoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in PAPA syndrome. Orthologous to human PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 18

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (26930956..26963473, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (26948578..26981095, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin filament binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in actin filament polymerization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in actin filament	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: proline-serine-threonine phosphatase-interacting protein 1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045216.1 → NP_001038681.1 proline-serine-threonine phosphatase-interacting protein 1a

Status: PROVISIONAL

Source sequence(s)

BX470164

UniProtKB/TrEMBL

A0A8M1NA82, Q1LX61

Related

ENSDARP00000080625.5, ENSDART00000086190.6

Conserved Domains (2) summary

cd07671
Location:15 → 258

F-BAR_PSTPIP1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Proline-Serine-Threonine Phosphatase-Interacting Protein 1

cd11824
Location:365 → 417

SH3_PSTPIP1; Src homology 3 domain of Proline-Serine-Threonine Phosphatase-Interacting Protein 1