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    uvssa UV-stimulated scaffold protein A [ Danio rerio (zebrafish) ]

    Gene ID: 402864, updated on 17-Sep-2024

    Summary

    Official Symbol
    uvssaprovided by ZNC
    Official Full Name
    UV-stimulated scaffold protein Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091204-111
    See related
    Ensembl:ENSDARG00000100916 AllianceGenome:ZFIN:ZDB-GENE-091204-111
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-18h19.2
    Summary
    Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in protein ubiquitination; response to UV; and transcription-coupled nucleotide-excision repair. Predicted to act upstream of or within DNA repair. Predicted to be active in chromosome. Human ortholog(s) of this gene implicated in UV-sensitive syndrome. Orthologous to human UVSSA (UV stimulated scaffold protein A). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See uvssa in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (15070796..15155384, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (14764929..14849811, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101882685 Neighboring gene uncharacterized LOC101882204 Neighboring gene NK1 transcription factor related 2-like,b Neighboring gene uncharacterized LOC108192158 Neighboring gene serine peptidase inhibitor, Kazal type 2, tandem duplicate 1 Neighboring gene serine peptidase inhibitor, Kazal type 2, tandem duplicate 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II complex binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in response to UV IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within response to UV IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to UV ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in transcription-coupled nucleotide-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transcription-coupled nucleotide-excision repair ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    UV-stimulated scaffold protein A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001346152.1NP_001333081.1  UV-stimulated scaffold protein A

      Status: VALIDATED

      Source sequence(s)
      BX119314, CR382342, EB910867
      UniProtKB/Swiss-Prot
      E7EXT2, F1QTE8, Q6PGZ1
      Related
      ENSDARP00000132945.1, ENSDART00000172666.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      15070796..15155384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)