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    ptc3 protein phosphatase PP2C catalytic subunit Ptc3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542008, updated on 14-Nov-2024

    Summary

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    Official Symbol
    ptc3
    Official Full Name
    protein phosphatase PP2C catalytic subunit Ptc3
    Primary source
    PomBase:SPAC2G11.07c
    Locus tag
    SPOM_SPAC2G11.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ptc3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (819768..821784, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene BRO1 domain-containing protein Neighboring gene ncRNA Neighboring gene AAA family ATPase Vps4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ca(2+) transporter Neighboring gene SMN complex subunit Smn1/Gem1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isoform-specific phosphorylation of fission yeast type 2C protein phosphatase. Kobayashi T, et al. Biochem Biophys Res Commun, 1998 Oct 9. PMID 9790950
    2. Protein phosphatase 2C acts independently of stress-activated kinase cascade to regulate the stress response in fission yeast. Gaits F, et al. J Biol Chem, 1997 Jul 11. PMID 9211944
    3. Counteractive roles of protein phosphatase 2C (PP2C) and a MAP kinase kinase homolog in the osmoregulation of fission yeast. Shiozaki K, et al. EMBO J, 1995 Feb 1. PMID 7859738, Free PMC Article
    4. Heat-shock-induced activation of stress MAP kinase is regulated by threonine- and tyrosine-specific phosphatases. Nguyen AN, et al. Genes Dev, 1999 Jul 1. PMID 10398679, Free PMC Article
    5. Atf1 is a target of the mitogen-activated protein kinase Pmk1 and regulates cell integrity in fission yeast. Takada H, et al. Mol Biol Cell, 2007 Dec. PMID 17881729, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables MAP kinase serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cation binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of p38MAPK cascade IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    protein phosphatase PP2C catalytic subunit Ptc3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      819768..821784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018485.3 → NP_593087.1  protein phosphatase PP2C catalytic subunit Ptc3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593087.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09173
      Conserved Domains (1) summary
      pfam00481
      Location:24 → 275
      PP2C; Protein phosphatase 2C
    Nucleotide Protein
    Heading Accession and Version

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