tyr.S tyrosinase S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Symbol: tyr.S
Full Name: tyrosinase S homeolog
Primary source: Xenbase:XB-GENE-988583
See related: AllianceGenome:Xenbase:XB-GENE-988583
Gene type: protein coding
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: tyr
Summary: Predicted to enable metal ion binding activity and tyrosinase activity. Predicted to act upstream of or within melanin biosynthetic process and pigmentation. Predicted to be located in melanosome membrane. Human ortholog(s) of this gene implicated in several diseases, including melanoma (multiple); ocular albinism 1; oculocutaneous albinism (multiple); retinoschisis; and vitiligo. Orthologous to human TYR (tyrosinase). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: not in current annotation release
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Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables tyrosinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within melanin biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within pigmentation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in melanosome membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info