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    GNMT glycine N-methyltransferase [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100009512, updated on 8-Mar-2024

    Summary

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    Gene symbol
    GNMT
    Gene description
    glycine N-methyltransferase
    See related
    Ensembl:ENSOCUG00000003858
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See GNMT in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 12 NC_067385.1 (123312918..123315557, complement)

    Chromosome 12 - NC_067385.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 2 regulatory subunit B'delta Neighboring gene peroxisomal biogenesis factor 6 Neighboring gene canopy FGF signaling regulator 3 Neighboring gene pre T cell antigen receptor alpha

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067385.1 Chromosome 12 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mammalian glycine N-methyltransferases. Comparative kinetic and structural properties of the enzymes from human, rat, rabbit and pig livers. Ogawa H, et al. Comp Biochem Physiol B, 1993 Nov. PMID 8281755
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables S-adenosyl-L-methionine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glycine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glycine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in S-adenosylhomocysteine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in S-adenosylmethionine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in one-carbon metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein homotetramerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of gluconeogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sarcosine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycine N-methyltransferase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067385.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      123312918..123315557 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002714413.4 → XP_002714459.1  glycine N-methyltransferase

      UniProtKB/Swiss-Prot
      G1SKJ7, Q29513
      Related
      ENSOCUP00000003341.2
      Conserved Domains (1) summary
      pfam12847
      Location:58 → 177
      Methyltransf_18; Methyltransferase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q29513.2 GenPept UniProtKB/Swiss-Prot:Q29513

    Gene LinkOut

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