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    VWF von Willebrand factor [ Odobenus rosmarus divergens (Pacific walrus) ]

    Gene ID: 101385961, updated on 8-Mar-2024

    Summary

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    Gene symbol
    VWF
    Gene description
    von Willebrand factor
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Odobenus rosmarus divergens (sub-species: divergens)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
    Orthologs
    human mouse all
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    Genomic context

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    See VWF in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    52
    Annotation release Status Assembly Chr Location
    101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004451058.1 (175517..306560, complement)

    NW_004451058.1Genomic Context describing neighboring genes Neighboring gene CD9 molecule Neighboring gene ATP-dependent RNA helicase DDX18 pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004451058.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-substrate adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    von Willebrand factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Oros_1.0 Primary Assembly

    Genomic

    1. NW_004451058.1 Reference Oros_1.0 Primary Assembly

      Range
      175517..306560 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012567186.1 → XP_012422640.1  von Willebrand factor isoform X2

      Conserved Domains (11) summary
      smart00041
      Location:2727 → 2808
      CT; C-terminal cystine knot-like domain (CTCK)
      smart00214
      Location:2431 → 2494
      VWC; von Willebrand factor (vWF) type C domain
      smart00216
      Location:377 → 540
      VWD; von Willebrand factor (vWF) type D domain
      smart00327
      Location:1277 → 1449
      VWA; von Willebrand factor (vWF) type A domain
      smart00832
      Location:1053 → 1127
      C8; This domain contains 8 conserved cysteine residues
      pfam00092
      Location:1498 → 1658
      VWA; von Willebrand factor type A domain
      pfam00094
      Location:35 → 179
      VWD; von Willebrand factor type D domain
      pfam01826
      Location:652 → 707
      TIL; Trypsin Inhibitor like cysteine rich domain
      pfam08742
      Location:580 → 648
      C8; C8 domain
      pfam16164
      Location:1198 → 1276
      VWA_N2; VWA N-terminal
      cl17735
      Location:350 → 394
      VWC; von Willebrand factor type C domain

    2. XM_004413880.2 → XP_004413937.1  von Willebrand factor isoform X1

      UniProtKB/TrEMBL
      A0A2U3WWK5
      Conserved Domains (11) summary
      smart00041
      Location:2727 → 2808
      CT; C-terminal cystine knot-like domain (CTCK)
      smart00214
      Location:2431 → 2494
      VWC; von Willebrand factor (vWF) type C domain
      smart00216
      Location:377 → 540
      VWD; von Willebrand factor (vWF) type D domain
      smart00327
      Location:1277 → 1449
      VWA; von Willebrand factor (vWF) type A domain
      smart00832
      Location:1053 → 1127
      C8; This domain contains 8 conserved cysteine residues
      pfam00092
      Location:1498 → 1658
      VWA; von Willebrand factor type A domain
      pfam00094
      Location:35 → 179
      VWD; von Willebrand factor type D domain
      pfam01826
      Location:652 → 707
      TIL; Trypsin Inhibitor like cysteine rich domain
      pfam08742
      Location:580 → 648
      C8; C8 domain
      pfam16164
      Location:1198 → 1276
      VWA_N2; VWA N-terminal
      cl17735
      Location:350 → 394
      VWC; von Willebrand factor type C domain
    Nucleotide Protein
    Heading Accession and Version

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