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    Fibin fin bud initiation factor homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499856, updated on 2-Nov-2024

    Summary

    Official Symbol
    Fibinprovided by RGD
    Official Full Name
    fin bud initiation factor homologprovided by RGD
    Primary source
    RGD:1563711
    See related
    EnsemblRapid:ENSRNOG00000073909 AllianceGenome:RGD:1563711
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable protein homodimerization activity. Predicted to be involved in protein kinase C signaling; response to dexamethasone; and response to manganese ion. Predicted to be located in endoplasmic reticulum. Orthologous to human FIBIN (fin bud initiation factor homolog). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See Fibin in Genome Data Viewer
    Location:
    3q34
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (117396973..117399244, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (96942405..96944676, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (101545207..101547478, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486420 Neighboring gene uncharacterized LOC120101622 Neighboring gene gamma-butyrobetaine hydroxylase 1 Neighboring gene solute carrier family 5 member 12 Neighboring gene anoctamin 3 Neighboring gene mucin 15, cell surface associated

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in protein kinase C signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to dexamethasone ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to manganese ion ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    fin bud initiation factor homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025042.2NP_001020213.1  fin bud initiation factor homolog precursor

      See identical proteins and their annotated locations for NP_001020213.1

      Status: VALIDATED

      Source sequence(s)
      BC085873, CK364593
      UniProtKB/Swiss-Prot
      Q5U2T4
      Related
      ENSRNOP00000102678.1, ENSRNOT00000143706.1
      Conserved Domains (1) summary
      pfam15819
      Location:15209
      Fibin; Fin bud initiation factor homologue

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      117396973..117399244 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)