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    PRPF4 pre-mRNA splicing tri-snRNP complex factor PRPF4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705934, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PRPF4provided by VGNC
    Official Full Name
    pre-mRNA splicing tri-snRNP complex factor PRPF4provided by VGNC
    Primary source
    VGNC:VGNC:76278
    See related
    Ensembl:ENSMMUG00000005844
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PRPF4 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (29545898..29564631, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (26113011..26129613, complement)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 31 Neighboring gene ring finger protein 183 Neighboring gene cell division cycle 26 Neighboring gene solute carrier family 31 member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables U4 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables U6 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U4/U6 x U5 tri-snRNP complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    U4/U6 small nuclear ribonucleoprotein Prp4
    Names
    PRP4 pre-mRNA processing factor 4 homolog
    pre-mRNA processing factor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261569.1 → NP_001248498.1  U4/U6 small nuclear ribonucleoprotein Prp4

      See identical proteins and their annotated locations for NP_001248498.1

      Status: PROVISIONAL

      Source sequence(s)
      JV048653
      UniProtKB/TrEMBL
      F6TT32, F6TT47, G7NG56
      Related
      ENSMMUP00000007706.4, ENSMMUT00000008195.4
      Conserved Domains (3) summary
      smart00500
      Location:102 → 140
      SFM; Splicing Factor Motif, present in Prp18 and Pr04
      cd00200
      Location:232 → 518
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:233 → 270
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      29545898..29564631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028834294.1 → XP_028690127.1  U4/U6 small nuclear ribonucleoprotein Prp4 isoform X1

      Conserved Domains (2) summary
      cd00200
      Location:8 → 276
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:42 → 78
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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