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    MAN2B1 mannosidase alpha class 2B member 1 [ Sus scrofa (pig) ]

    Gene ID: 100518647, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MAN2B1provided by VGNC
    Official Full Name
    mannosidase alpha class 2B member 1provided by VGNC
    Primary source
    VGNC:VGNC:100165
    See related
    Ensembl:ENSSSCG00000013720
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in spleen (RPKM 128.0), lung (RPKM 60.8) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See MAN2B1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 2 NC_010444.4 (66329051..66347051)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 2 NC_010444.3 (66706800..66724791)

    Chromosome 2 - NC_010444.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100736972 Neighboring gene deoxyhypusine synthase Neighboring gene WD repeat domain 83 opposite strand Neighboring gene WD repeat domain 83 Neighboring gene zinc finger protein 791-like Neighboring gene zinc finger protein 709-like Neighboring gene zinc finger protein 709-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alpha-mannosidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mannose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lysosomal alpha-mannosidase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010444.4 Reference Sscrofa11.1 Primary Assembly

      Range
      66329051..66347051
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003123314.4 → XP_003123362.2  lysosomal alpha-mannosidase isoform X2

      UniProtKB/TrEMBL
      K9J4R3
      Related
      ENSSSCP00000014590.4, ENSSSCT00000014994.5
      Conserved Domains (2) summary
      PLN02701
      Location:47 → 998
      PLN02701; alpha-mannosidase
      cd10810
      Location:64 → 342
      GH38N_AMII_LAM_like; N-terminal catalytic domain of lysosomal alpha-mannosidase and similar proteins; glycoside hydrolase family 38 (GH38)

    2. XM_013990604.2 → XP_013846058.2  lysosomal alpha-mannosidase isoform X1

      UniProtKB/TrEMBL
      K9J4R3
      Conserved Domains (2) summary
      PLN02701
      Location:47 → 1009
      PLN02701; alpha-mannosidase
      cd10810
      Location:64 → 342
      GH38N_AMII_LAM_like; N-terminal catalytic domain of lysosomal alpha-mannosidase and similar proteins; glycoside hydrolase family 38 (GH38)
    Nucleotide Protein Strain
    Heading Accession and Version

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