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    kmt2d lysine (K)-specific methyltransferase 2D [ Gadus morhua (Atlantic cod) ]

    Gene ID: 115547788, updated on 17-Mar-2024

    Summary

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    Gene symbol
    kmt2d
    Gene description
    lysine (K)-specific methyltransferase 2D
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gadus morhua
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Gadidae; Gadus
    Orthologs
    human zebrafish all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    56
    Annotation release Status Assembly Chr Location
    100 current gadMor3.0 (GCF_902167405.1) 1 NC_044048.1 (8023223..8054462, complement)

    Chromosome 1 - NC_044048.1Genomic Context describing neighboring genes Neighboring gene activin A receptor like type 1 Neighboring gene activin A receptor type 1Ba Neighboring gene desert hedgehog signaling molecule Neighboring gene limb development membrane protein 1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_044048.1 Chromosome 1 Reference gadMor3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Photoperiod influences growth and mll (mixed-lineage leukaemia) expression in Atlantic cod. Nagasawa K, et al. PLoS One, 2012. PMID 22590633, Free PMC Article
    2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nBAF complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone-lysine N-methyltransferase 2D
    Names
    lysine methyltransferase 2D
    myeloid/lymphoid or mixed-lineage leukemia 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gadus morhua Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference gadMor3.0 Primary Assembly

    Genomic

    1. NC_044048.1 Reference gadMor3.0 Primary Assembly

      Range
      8023223..8054462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030362252.1 → XP_030218112.1  histone-lysine N-methyltransferase 2D isoform X2

      Conserved Domains (16) summary
      TIGR01628
      Location:2820 → 2930
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      smart00398
      Location:1496 → 1551
      HMG; high mobility group
      smart00249
      Location:347 → 391
      PHD; PHD zinc finger
      PHA03247
      Location:1545 → 2017
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:4490 → 4614
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      PRK13108
      Location:392 → 565
      PRK13108; prolipoprotein diacylglyceryl transferase; Reviewed
      cd15509
      Location:219 → 263
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15513
      Location:906 → 952
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:855 → 905
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:983 → 1033
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3201 → 3532
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam05964
      Location:4809 → 4860
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:4866 → 4950
      FYRC; F/Y rich C-terminus
      pfam09770
      Location:2274 → 2431
      PAT1; Topoisomerase II-associated protein PAT1
      cd19171
      Location:5012 → 5164
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl22851
      Location:4660 → 4766
      PHD_SF; PHD finger superfamily

    2. XM_030362261.1 → XP_030218121.1  histone-lysine N-methyltransferase 2D isoform X3

      Conserved Domains (16) summary
      TIGR01628
      Location:2821 → 2931
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      smart00398
      Location:1496 → 1551
      HMG; high mobility group
      smart00249
      Location:347 → 391
      PHD; PHD zinc finger
      PHA03247
      Location:1567 → 2018
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:4484 → 4608
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      PRK13108
      Location:392 → 565
      PRK13108; prolipoprotein diacylglyceryl transferase; Reviewed
      cd15509
      Location:219 → 263
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15513
      Location:906 → 952
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:855 → 905
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:983 → 1033
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3202 → 3533
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam05964
      Location:4803 → 4854
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:4860 → 4944
      FYRC; F/Y rich C-terminus
      pfam09770
      Location:2275 → 2432
      PAT1; Topoisomerase II-associated protein PAT1
      cd19171
      Location:5006 → 5158
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl22851
      Location:4654 → 4760
      PHD_SF; PHD finger superfamily

    3. XM_030362241.1 → XP_030218101.1  histone-lysine N-methyltransferase 2D isoform X1

      Conserved Domains (16) summary
      TIGR01628
      Location:2821 → 2931
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      smart00398
      Location:1496 → 1551
      HMG; high mobility group
      smart00249
      Location:347 → 391
      PHD; PHD zinc finger
      PHA03247
      Location:1567 → 2018
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:4491 → 4615
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      PRK13108
      Location:392 → 565
      PRK13108; prolipoprotein diacylglyceryl transferase; Reviewed
      cd15509
      Location:219 → 263
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15513
      Location:906 → 952
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:855 → 905
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:983 → 1033
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3202 → 3533
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam05964
      Location:4810 → 4861
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:4867 → 4951
      FYRC; F/Y rich C-terminus
      pfam09770
      Location:2275 → 2432
      PAT1; Topoisomerase II-associated protein PAT1
      cd19171
      Location:5013 → 5165
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl22851
      Location:4661 → 4767
      PHD_SF; PHD finger superfamily

    4. XM_030362246.1 → XP_030218106.1  histone-lysine N-methyltransferase 2D isoform X1

      Conserved Domains (16) summary
      TIGR01628
      Location:2821 → 2931
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      smart00398
      Location:1496 → 1551
      HMG; high mobility group
      smart00249
      Location:347 → 391
      PHD; PHD zinc finger
      PHA03247
      Location:1567 → 2018
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:4491 → 4615
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      PRK13108
      Location:392 → 565
      PRK13108; prolipoprotein diacylglyceryl transferase; Reviewed
      cd15509
      Location:219 → 263
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15513
      Location:906 → 952
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:855 → 905
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:983 → 1033
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3202 → 3533
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam05964
      Location:4810 → 4861
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:4867 → 4951
      FYRC; F/Y rich C-terminus
      pfam09770
      Location:2275 → 2432
      PAT1; Topoisomerase II-associated protein PAT1
      cd19171
      Location:5013 → 5165
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl22851
      Location:4661 → 4767
      PHD_SF; PHD finger superfamily
    Nucleotide Protein
    Heading Accession and Version

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