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    PDK1 pyruvate dehydrogenase kinase 1 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 459743, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PDK1provided by VGNC
    Official Full Name
    pyruvate dehydrogenase kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:6370
    Locus tag
    CK820_G0001488
    See related
    Ensembl:ENSPTRG00000012642
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See PDK1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (74603823..74772969)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (74603797..74765158)

    Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107973828 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC104005263 Neighboring gene integrin subunit alpha 6 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC107973830 Neighboring gene Rap guanine nucleotide exchange factor 4 Neighboring gene mitogen-activated protein kinase kinase kinase 20 Neighboring gene uncharacterized LOC129143420

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of glucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial
    Names
    pyruvate dehydrogenase kinase, isozyme 1
    XP_001147224.2
    XP_009442041.1
    XP_515910.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      74603823..74772969
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_515910.8 → XP_515910.3  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X3

      See identical proteins and their annotated locations for XP_515910.3

      UniProtKB/TrEMBL
      A0A2J8PQY5, A0A6D2WTQ5, H2QIZ6
      Related
      ENSPTRP00000021603.4
      Conserved Domains (2) summary
      smart00387
      Location:270 → 390
      HATPase_c; Histidine kinase-like ATPases
      pfam10436
      Location:56 → 220
      BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

    2. XM_009443766.5 → XP_009442041.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X1

      Conserved Domains (3) summary
      smart00387
      Location:290 → 411
      HATPase_c; Histidine kinase-like ATPases
      COG0642
      Location:279 → 411
      BaeS; Signal transduction histidine kinase [Signal transduction mechanisms]
      pfam10436
      Location:56 → 240
      BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

    3. XM_001147224.7 → XP_001147224.2  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X2

      See identical proteins and their annotated locations for XP_001147224.2

      UniProtKB/TrEMBL
      A0A2I3RKX1, A0A2J8PQZ1, A0A6D2XMI8
      Related
      ENSPTRP00000065011.1
      Conserved Domains (2) summary
      smart00387
      Location:290 → 410
      HATPase_c; Histidine kinase-like ATPases
      pfam10436
      Location:56 → 240
      BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

    RNA

    1. XR_010150152.1 RNA Sequence

    2. XR_010150149.1 RNA Sequence

    3. XR_010150153.1 RNA Sequence

    4. XR_010150150.1 RNA Sequence

    5. XR_010150151.1 RNA Sequence

    6. XR_010150147.1 RNA Sequence

    7. XR_010150148.1 RNA Sequence

    8. XR_010150140.1 RNA Sequence

    9. XR_008546826.2 RNA Sequence

    10. XR_001716307.3 RNA Sequence

    11. XR_008546819.2 RNA Sequence

    12. XR_010150135.1 RNA Sequence

    13. XR_001716308.4 RNA Sequence

    14. XR_001716309.4 RNA Sequence

    15. XR_008546823.2 RNA Sequence

    16. XR_008546831.2 RNA Sequence

    17. XR_008546824.2 RNA Sequence

    18. XR_010150137.1 RNA Sequence

    19. XR_010150138.1 RNA Sequence

    20. XR_008546828.2 RNA Sequence

    21. XR_010150139.1 RNA Sequence

    22. XR_010150154.1 RNA Sequence

    23. XR_001716303.4 RNA Sequence

    24. XR_678509.4 RNA Sequence

    25. XR_001716306.3 RNA Sequence

    26. XR_008546825.2 RNA Sequence

    27. XR_008546830.2 RNA Sequence

    28. XR_001716311.4 RNA Sequence

    29. XR_678508.5 RNA Sequence

    30. XR_010150136.1 RNA Sequence

    31. XR_008546827.2 RNA Sequence

    32. XR_678510.5 RNA Sequence

    33. XR_010150145.1 RNA Sequence

    34. XR_010150155.1 RNA Sequence

    35. XR_010150144.1 RNA Sequence

    36. XR_008546838.2 RNA Sequence

    37. XR_008546836.2 RNA Sequence

    38. XR_008546835.2 RNA Sequence

    39. XR_678511.4 RNA Sequence

    40. XR_008546834.2 RNA Sequence

    41. XR_008546833.2 RNA Sequence

    42. XR_010150146.1 RNA Sequence

    43. XR_010150143.1 RNA Sequence

    44. XR_008546837.2 RNA Sequence

    45. XR_010150141.1 RNA Sequence

    46. XR_010150142.1 RNA Sequence

    47. XR_008546832.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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