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    KMT2E lysine methyltransferase 2E (inactive) [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100173903, updated on 3-Apr-2024

    Summary

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    Gene symbol
    KMT2E
    Gene description
    lysine methyltransferase 2E (inactive)
    Locus tag
    CR201_G0018070
    See related
    Ensembl:ENSPPYG00000017888
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Also known as
    MLL5
    Orthologs
    human mouse all
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    Genomic context

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    See KMT2E in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 6 NC_071991.2 (101721205..101823889)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 7 NC_071992.1 (95543770..95646445)

    Chromosome 6 - NC_071991.2Genomic Context describing neighboring genes Neighboring gene origin recognition complex subunit 5 Neighboring gene LHFPL tetraspan subfamily member 3 Neighboring gene uncharacterized LOC103891186 Neighboring gene SRSF protein kinase 2 Neighboring gene large ribosomal subunit protein eL36-like Neighboring gene RWD domain-containing protein 4-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp459J0914

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables methylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Rpd3L-Expanded complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of Set3 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inactive histone-lysine N-methyltransferase 2E
    Names
    myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071991.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      101721205..101823889
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002818325.6 → XP_002818371.3  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53
      Related
      ENSPPYP00000020053.3
      Conserved Domains (7) summary
      smart00317
      Location:343 → 452
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd15550
      Location:120 → 163
      PHD_MLL5; PHD finger found in mixed lineage leukemia 5 (MLL5)
      pfam03326
      Location:1288 → 1524
      Herpes_TAF50; Herpesvirus transcription activation factor (transactivator)
      pfam09606
      Location:1463 → 1828
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl25549
      Location:550 → 605
      ARGLU; Arginine and glutamate-rich 1
      cl25742
      Location:561 → 669
      ERM; Ezrin/radixin/moesin family
      cl26464
      Location:1740 → 1845
      Atrophin-1; Atrophin-1 family

    2. XM_054560595.2 → XP_054416570.1  inactive histone-lysine N-methyltransferase 2E isoform X2

    3. XM_054560591.2 → XP_054416566.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    4. XM_054560593.2 → XP_054416568.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    5. XM_054560594.2 → XP_054416569.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    6. XM_054560589.2 → XP_054416564.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    7. XM_054560590.2 → XP_054416565.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    8. XM_024250259.3 → XP_024106027.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53
      Conserved Domains (7) summary
      smart00317
      Location:343 → 452
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd15550
      Location:120 → 163
      PHD_MLL5; PHD finger found in mixed lineage leukemia 5 (MLL5)
      pfam03326
      Location:1288 → 1524
      Herpes_TAF50; Herpesvirus transcription activation factor (transactivator)
      pfam09606
      Location:1463 → 1828
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl25549
      Location:550 → 605
      ARGLU; Arginine and glutamate-rich 1
      cl25742
      Location:561 → 669
      ERM; Ezrin/radixin/moesin family
      cl26464
      Location:1740 → 1845
      Atrophin-1; Atrophin-1 family

    9. XM_063725761.1 → XP_063581831.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    10. XM_054560597.1 → XP_054416572.1  inactive histone-lysine N-methyltransferase 2E isoform X3

    Nucleotide Protein
    Heading Accession and Version

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