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    GRK4 G protein-coupled receptor kinase 4 [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100442141, updated on 6-Jun-2024

    Summary

    Gene symbol
    GRK4
    Gene description
    G protein-coupled receptor kinase 4
    Locus tag
    CR201_G0040849
    See related
    Ensembl:ENSPPYG00000014550
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 3
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 3 NC_071988.2 (2997802..3077955)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 4 NC_071989.1 (2995874..3076666)

    Chromosome 3 - NC_071988.2Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 10 Neighboring gene NOP14 nucleolar protein Neighboring gene uncharacterized LOC129059227 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC103890357

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables G protein-coupled receptor kinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    G protein-coupled receptor kinase 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071988.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      2997802..3077955
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063723281.1XP_063579351.1  G protein-coupled receptor kinase 4 isoform X8

      UniProtKB/TrEMBL
      A0A8I5UYJ2
    2. XM_063723282.1XP_063579352.1  G protein-coupled receptor kinase 4 isoform X10

      UniProtKB/TrEMBL
      A0A8I5UYJ2
    3. XM_054554949.2XP_054410924.1  G protein-coupled receptor kinase 4 isoform X12

      UniProtKB/TrEMBL
      A0A2J8SRQ3, A0A8I5UYJ2, H2PCR5
    4. XM_054554948.2XP_054410923.1  G protein-coupled receptor kinase 4 isoform X12

      UniProtKB/TrEMBL
      A0A2J8SRQ3, A0A8I5UYJ2, H2PCR5
    5. XM_054554956.2XP_054410931.1  G protein-coupled receptor kinase 4 isoform X17

      UniProtKB/TrEMBL
      A0A2J8SRL5, A0A8I5T0A4, A0A8I5UYJ2
    6. XM_054554952.2XP_054410927.1  G protein-coupled receptor kinase 4 isoform X15

      UniProtKB/TrEMBL
      A0A2J8SRP2, A0A8I5TZH9, A0A8I5UYJ2
    7. XM_054554953.2XP_054410928.1  G protein-coupled receptor kinase 4 isoform X15

      UniProtKB/TrEMBL
      A0A2J8SRP2, A0A8I5TZH9, A0A8I5UYJ2
    8. XM_063723285.1XP_063579355.1  G protein-coupled receptor kinase 4 isoform X18

      UniProtKB/TrEMBL
      A0A2J8SRM6, A0A8I5UYJ2
    9. XM_063723280.1XP_063579350.1  G protein-coupled receptor kinase 4 isoform X8

      UniProtKB/TrEMBL
      A0A8I5UYJ2
    10. XM_063723283.1XP_063579353.1  G protein-coupled receptor kinase 4 isoform X10

      UniProtKB/TrEMBL
      A0A8I5UYJ2
    11. XM_063723286.1XP_063579356.1  G protein-coupled receptor kinase 4 isoform X19

    12. XM_054554960.2XP_054410935.1  G protein-coupled receptor kinase 4 isoform X20

    13. XM_054554966.2XP_054410941.1  G protein-coupled receptor kinase 4 isoform X21

    14. XM_054554962.2XP_054410937.1  G protein-coupled receptor kinase 4 isoform X21

    15. XM_063723278.1XP_063579348.1  G protein-coupled receptor kinase 4 isoform X1

    16. XM_063723279.1XP_063579349.1  G protein-coupled receptor kinase 4 isoform X2

    17. XM_054554940.2XP_054410915.1  G protein-coupled receptor kinase 4 isoform X3

    18. XM_054554942.2XP_054410917.1  G protein-coupled receptor kinase 4 isoform X5

    19. XM_054554950.2XP_054410925.1  G protein-coupled receptor kinase 4 isoform X13

      UniProtKB/TrEMBL
      A0A8I5UYJ2
    20. XM_054554943.2XP_054410918.1  G protein-coupled receptor kinase 4 isoform X6

      UniProtKB/TrEMBL
      A0A8I5UYJ2
    21. XM_054554951.2XP_054410926.1  G protein-coupled receptor kinase 4 isoform X14

      UniProtKB/TrEMBL
      A0A8I5UYJ2
    22. XM_054554941.2XP_054410916.1  G protein-coupled receptor kinase 4 isoform X4

    23. XM_054554945.2XP_054410920.1  G protein-coupled receptor kinase 4 isoform X9

    24. XM_054554955.2XP_054410930.1  G protein-coupled receptor kinase 4 isoform X16

      UniProtKB/TrEMBL
      A0A8I5UYJ2
    25. XM_054554944.2XP_054410919.1  G protein-coupled receptor kinase 4 isoform X7

    26. XM_054554947.2XP_054410922.1  G protein-coupled receptor kinase 4 isoform X11

    27. XM_054554961.1XP_054410936.1  G protein-coupled receptor kinase 4 isoform X20

    28. XM_054554963.1XP_054410938.1  G protein-coupled receptor kinase 4 isoform X21

    29. XM_024246469.3XP_024102237.1  G protein-coupled receptor kinase 4 isoform X20

      Conserved Domains (1) summary
      cl21453
      Location:5276
      PKc_like; Protein Kinases, catalytic domain