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    CHUK component of inhibitor of nuclear factor kappa B kinase complex [ Eptesicus fuscus (big brown bat) ]

    Gene ID: 103288473, updated on 30-Mar-2024

    Summary

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    Gene symbol
    CHUK
    Gene description
    component of inhibitor of nuclear factor kappa B kinase complex
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Eptesicus fuscus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Eptesicus
    Orthologs
    human mouse all
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    Genomic context

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    See CHUK in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2023_03 current DD_ASM_mEF_20220401 (GCF_027574615.1) 17 NC_072489.1 (42418846..42459402, complement)
    101 previous assembly EptFus1.0 (GCF_000308155.1) Unplaced Scaffold NW_007370676.1 (4157011..4197820, complement)

    Chromosome 17 - NC_072489.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 2C44-like Neighboring gene ER lipid raft associated 1 Neighboring gene small nucleolar RNA SNORA12 Neighboring gene CWF19 like cell cycle control factor 1 Neighboring gene biogenesis of lysosomal organelles complex 1 subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables IkappaB kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tumor necrosis factor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of IkappaB kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inhibitor of nuclear factor kappa-B kinase subunit alpha
    Names
    conserved helix-loop-helix ubiquitous kinase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_027574615.1-RS_2023_03

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference DD_ASM_mEF_20220401

    Genomic

    1. NC_072489.1 Reference DD_ASM_mEF_20220401

      Range
      42418846..42459402 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054729314.1 → XP_054585289.1  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X3

    2. XM_028149202.2 → XP_028005003.2  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X2

    3. XM_008144178.3 → XP_008142400.2  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1

    4. XM_054729315.1 → XP_054585290.1  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X4

    RNA

    1. XR_008558827.1 RNA Sequence

    2. XR_008558826.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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