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    CTSB cathepsin B [ Artibeus jamaicensis (Jamaican fruit-eating bat) ]

    Gene ID: 119049448, updated on 30-Mar-2024

    Summary

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    Gene symbol
    CTSB
    Gene description
    cathepsin B
    See related
    EnsemblRapid:ENSAJMG00005012275
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Artibeus jamaicensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Stenodermatinae; Artibeus
    Orthologs
    human mouse all
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    Genomic context

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    See CTSB in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_03 current CSHL_Jam_final (GCF_021234435.1) Unplaced Scaffold NW_026522047.1 (35639353..35658637)

    NW_026522047.1Genomic Context describing neighboring genes Neighboring gene defensin beta 134 Neighboring gene defensin beta 136 Neighboring gene farnesyl-diphosphate farnesyltransferase 1 Neighboring gene uncharacterized LOC128626367

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_026522047 Unplaced Scaffold Reference CSHL_Jam_final Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cathepsin B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_021234435.1-RS_2023_03

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CSHL_Jam_final Primary Assembly

    Genomic

    1. NW_026522047.1 Reference CSHL_Jam_final Primary Assembly

      Range
      35639353..35658637
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_037145435.2 → XP_037001330.1  cathepsin B isoform X1

      Related
      ENSAJMP00005017550.1
      Conserved Domains (2) summary
      cd02620
      Location:81 → 329
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
      pfam08127
      Location:26 → 65
      Propeptide_C1; Peptidase family C1 propeptide

    2. XM_037145436.2 → XP_037001331.1  cathepsin B isoform X2

      Conserved Domains (1) summary
      cd02620
      Location:25 → 205
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    Nucleotide Protein
    Heading Accession and Version

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