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    ARHGEF25 Rho guanine nucleotide exchange factor 25 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100339852, updated on 10-Oct-2024

    Summary

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    Gene symbol
    ARHGEF25
    Gene description
    Rho guanine nucleotide exchange factor 25
    See related
    Ensembl:ENSOCUG00000014113
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGEF25 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259166.1 (3336290..3342993, complement)

    NW_026259166.1Genomic Context describing neighboring genes Neighboring gene beta-1,4-N-acetyl-galactosaminyltransferase 1 Neighboring gene Solute carrier family 26 member 10 Neighboring gene uncharacterized LOC127487429 Neighboring gene deltex E3 ubiquitin ligase 3 Neighboring gene phosphatidylinositol-5-phosphate 4-kinase type 2 gamma Neighboring gene uncharacterized LOC127487430

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_026259166 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho guanine nucleotide exchange factor 25
    Names
    Rho guanine nucleotide exchange factor (GEF) 25
    RhoA/RAC/CDC42 exchange factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NW_026259166.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      3336290..3342993 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008274224.3 → XP_008272446.1  rho guanine nucleotide exchange factor 25 isoform X2

      UniProtKB/TrEMBL
      A0A5F9CL98
      Conserved Domains (2) summary
      cd13241
      Location:368 → 510
      PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
      pfam00621
      Location:193 → 364
      RhoGEF; RhoGEF domain

    2. XM_002720920.4 → XP_002720966.1  rho guanine nucleotide exchange factor 25 isoform X1

      UniProtKB/TrEMBL
      A0A5F9CL98, A0A5F9D4Z8
      Related
      ENSOCUP00000040425.1
      Conserved Domains (2) summary
      cd13241
      Location:378 → 520
      PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
      pfam00621
      Location:203 → 374
      RhoGEF; RhoGEF domain

    3. XM_017350488.2 → XP_017205977.1  rho guanine nucleotide exchange factor 25 isoform X3

      UniProtKB/TrEMBL
      A0A5F9CL98, G1T6R3
      Related
      ENSOCUP00000012127.3

    4. XM_017350486.2 → XP_017205975.1  rho guanine nucleotide exchange factor 25 isoform X3

      UniProtKB/TrEMBL
      A0A5F9CL98, G1T6R3

    5. XM_051832963.1 → XP_051688923.1  rho guanine nucleotide exchange factor 25 isoform X3

      UniProtKB/TrEMBL
      G1T6R3
    Nucleotide Protein
    Heading Accession and Version

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