U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    LOC127405771 OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31163380-31164262 [ Homo sapiens (human) ]

    Gene ID: 127405771, updated on 12-Sep-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    LOC127405771
    Gene description
    OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31163380-31164262
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 transcription factor and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See LOC127405771 in Genome Data Viewer
    Location:
    chromosome: 6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (31195603..31196485)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (31063301..31064183)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (31163380..31164262)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr6:31132319-31132900 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr6:31135533-31136390 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:31136391-31137248 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:31137249-31138106 Neighboring gene POU5F1 5' regulatory region Neighboring gene POU class 5 homeobox 1 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31142488-31143384 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31145628-31146222 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31146755-31147256 Neighboring gene psoriasis susceptibility 1 candidate 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31148363-31148906 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31153427-31154016 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31154017-31154604 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31158168-31158669 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31166400-31167283 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31167284-31168166 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31169734-31170274 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31170275-31170813 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:31170972-31171692 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr6:31171693-31172412 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr6:31172413-31173132 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr6:31173133-31173851 Neighboring gene HLA complex group 27 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31178749-31179743 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:31180245-31180430 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31183567-31184468 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31190777-31191278 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31192075-31192697 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31192791-31193386 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31196240-31196741 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31197314-31197823 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31203152-31203653 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31207427-31207928 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr6:31212376-31213125 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31213660-31214161 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31217950-31218451 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31220759-31221378 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31221379-31221998 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31222367-31223043 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31227633-31228239 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31228743-31229244 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31234264-31235207 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31235343-31235902 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31236021-31236522 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31237308-31237809 Neighboring gene major histocompatibility complex, class I, C

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

    Go to the top of the page Help

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See Variation Viewer (GRCh37.p13)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_107742.1 

      Range
      101..983
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      31195603..31196485
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_2

    Genomic

    1. NT_113891.3 Reference GRCh38.p14 ALT_REF_LOCI_2

      Range
      2678049..2678931
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_3

    Genomic

    1. NT_167245.2 Reference GRCh38.p14 ALT_REF_LOCI_3

      Range
      2454937..2455819
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_7

    Genomic

    1. NT_167249.2 Reference GRCh38.p14 ALT_REF_LOCI_7

      Range
      2499027..2499909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      31063301..31064183
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases