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    LOC127276231 NANOG hESC enhancer GRCh37_chr2:237874235-237874736 [ Homo sapiens (human) ]

    Gene ID: 127276231, updated on 27-Aug-2024

    Summary

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    Gene symbol
    LOC127276231
    Gene description
    NANOG hESC enhancer GRCh37_chr2:237874235-237874736
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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    Genomic context

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    Location:
    chromosome: 2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (236965592..236966093)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (237456729..237457234)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373949 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:237682540-237683040 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:237683041-237683541 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:237701553-237702280 Neighboring gene uncharacterized LOC107986002 Neighboring gene NANOG hESC enhancer GRCh37_chr2:237719656-237720238 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:237726720-237727220 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:237818251-237818750 Neighboring gene Sharpr-MPRA regulatory region 6837 Neighboring gene COPS8 divergent transcript Neighboring gene Sharpr-MPRA regulatory region 9900 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:237877273-237877772 Neighboring gene RNA, U6 small nuclear 1051, pseudogene Neighboring gene uncharacterized LOC105373950 Neighboring gene uncharacterized LOC93463

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_098075.1 

      Range
      101..602
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      236965592..236966093
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      237456729..237457234
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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