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    NEU3 neuraminidase 3 [ Gallus gallus (chicken) ]

    Gene ID: 430542, updated on 6-Jun-2024

    Summary

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    Official Symbol
    NEU3provided by CGNC
    Official Full Name
    neuraminidase 3provided by CGNC
    Primary source
    CGNC:66584
    See related
    Ensembl:ENSGALG00010001886
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See NEU3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (194739342..194744054)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (194608392..194612480)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene chordin like 2 Neighboring gene ring finger protein 169 Neighboring gene X-ray radiation resistance associated 1 Neighboring gene signal peptidase complex subunit 2 Neighboring gene prolyl 4-hydroxylase subunit alpha 3 Neighboring gene protein phosphatase methylesterase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops. Giacopuzzi E, et al. BMC Biochem, 2011 Aug 23. PMID 21861893, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. features of the evolving loops in NEU3
      Title: Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables exo-alpha-sialidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ganglioside catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in oligosaccharide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sialidase-3
    Names
    membrane-bound sialidase
    sialidase 3 (membrane sialidase)
    NP_001305946.3
    XP_015136494.2
    XP_015136495.2
    XP_015136497.2
    XP_040557624.1
    XP_046764558.1
    XP_046764559.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001319017.3 → NP_001305946.3  sialidase-3

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000032
      UniProtKB/TrEMBL
      G4V263
      Conserved Domains (1) summary
      cd15482
      Location:30 → 344
      Sialidase_non-viral; Non-viral sialidases

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      194739342..194744054
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015281008.4 → XP_015136494.2  sialidase-3 isoform X3

      UniProtKB/TrEMBL
      A0A8V0X3Z6, A0A8V0X7I5
      Related
      ENSGALP00010002597.1, ENSGALT00010004309.1
      Conserved Domains (1) summary
      cd15482
      Location:43 → 357
      Sialidase_non-viral; Non-viral sialidases

    2. XM_015281011.3 → XP_015136497.2  sialidase-3 isoform X1

      UniProtKB/TrEMBL
      G4V263
      Conserved Domains (1) summary
      cd15482
      Location:30 → 344
      Sialidase_non-viral; Non-viral sialidases

    3. XM_040701690.2 → XP_040557624.1  sialidase-3 isoform X4

      UniProtKB/TrEMBL
      A0A8V0X7I5
      Conserved Domains (1) summary
      cd15482
      Location:58 → 372
      Sialidase_non-viral; Non-viral sialidases

    4. XM_015281009.4 → XP_015136495.2  sialidase-3 isoform X2

      UniProtKB/TrEMBL
      G4V263
      Conserved Domains (1) summary
      cd15482
      Location:58 → 372
      Sialidase_non-viral; Non-viral sialidases

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      194608392..194612480
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046908602.1 → XP_046764558.1  sialidase-3 isoform X1

      UniProtKB/TrEMBL
      G4V263

    2. XM_046908603.1 → XP_046764559.1  sialidase-3 isoform X5

      UniProtKB/TrEMBL
      I6LL52
    Nucleotide Protein
    Heading Accession and Version

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