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    Fmr1nb Fmr1 neighbor [ Mus musculus (house mouse) ]

    Gene ID: 207854, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Fmr1nbprovided by MGI
    Official Full Name
    Fmr1 neighborprovided by MGI
    Primary source
    MGI:MGI:2672032
    See related
    Ensembl:ENSMUSG00000062170 AllianceGenome:MGI:2672032
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NYSAR35; NY-SAR-35; 3830422N12Rik
    Summary
    Predicted to be located in membrane. Is expressed in reproductive system. Orthologous to human FMR1NB (FMR1 neighbor). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward placenta adult (RPKM 77.3) See more
    Orthologs
    human all
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    Genomic context

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    See Fmr1nb in Genome Data Viewer
    Location:
    X A7.1; X 34.86 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (67805460..67848167)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (68761839..68804561)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene FMRP translational regulator 1, opposite strand Neighboring gene fragile X messenger ribonucleoprotein 1 Neighboring gene STARR-seq mESC enhancer starr_47302 Neighboring gene serine/threonine/tyrosine interacting protein, pseudogene Neighboring gene predicted gene 6812

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Reverse genetics reveals single gene of every candidate on Hybrid sterility, X Chromosome QTL 2 (Hstx2) are dispensable for spermatogenesis. Morimoto K, et al. Sci Rep, 2020 Jun 3. PMID 32493902, Free PMC Article
    2. Immunomic analysis of human sarcoma. Lee SY, et al. Proc Natl Acad Sci U S A, 2003 Mar 4. PMID 12601173, Free PMC Article
    3. Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Miyata H, et al. Proc Natl Acad Sci U S A, 2016 Jul 12. PMID 27357688, Free PMC Article
    4. A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Breslow DK, et al. Nat Genet, 2018 Mar. PMID 29459677, Free PMC Article
    5. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC117577

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fmr1 neighbor protein
    Names
    protein mNY-SAR-35

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166619.2 → NP_001160091.1  fmr1 neighbor protein isoform 2

      See identical proteins and their annotated locations for NP_001160091.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon in the 5' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.
      Source sequence(s)
      AC055766
      Consensus CDS
      CCDS53084.1
      UniProtKB/Swiss-Prot
      B2RQU9, Q4KL61, Q80ZA7, Q8BPD4
      Related
      ENSMUSP00000064543.6, ENSMUST00000069731.12

    2. NM_001166620.2 → NP_001160092.1  fmr1 neighbor protein isoform 3

      See identical proteins and their annotated locations for NP_001160092.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two alternate exons, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1.
      Source sequence(s)
      AC055766
      Consensus CDS
      CCDS53085.1
      UniProtKB/TrEMBL
      B7ZW84
      Related
      ENSMUSP00000110294.2, ENSMUST00000114647.8

    3. NM_174993.3 → NP_778158.2  fmr1 neighbor protein isoform 1

      See identical proteins and their annotated locations for NP_778158.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1).
      Source sequence(s)
      AC055766
      Consensus CDS
      CCDS30172.1
      UniProtKB/Swiss-Prot
      B2RQU9, Q4KL61, Q80ZA7, Q8BPD4
      UniProtKB/TrEMBL
      B7ZNB2, B7ZWA0
      Related
      ENSMUSP00000071748.7, ENSMUST00000071848.7

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      67805460..67848167
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80ZA7.1 GenPept UniProtKB/Swiss-Prot:Q80ZA7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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