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    Yif1b Yip1 interacting factor homolog B, membrane trafficking protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292768, updated on 17-Aug-2024

    Summary

    Symbol
    Yif1bprovided by RGD
    Full Name
    Yip1 interacting factor homolog B, membrane trafficking proteinprovided by RGD
    Primary source
    RGD:735199
    See related
    EnsemblRapid:ENSRNOG00000055286 AllianceGenome:RGD:735199
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Yip1b
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; protein targeting to membrane; and sperm axoneme assembly. Located in Golgi apparatus; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human YIF1B (Yip1 interacting factor homolog B, membrane trafficking protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 118.1), Kidney (RPKM 106.5) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Yif1b in Genome Data Viewer
    Location:
    1q21
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (93667113..93677381)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (84539673..84549906)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (88182379..88192568)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene MARCKS-related protein-like Neighboring gene cation channel sperm associated auxiliary subunit gamma Neighboring gene similar to human chromosome 19 open reading frame 33 Neighboring gene potassium two pore domain channel subfamily K member 6 Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14A Neighboring gene serine peptidase inhibitor, Kunitz type, 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC72987

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein targeting to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein targeting to membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sperm flagellum assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sperm flagellum assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum-Golgi intermediate compartment IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein YIF1B
    Names
    YIP1-interacting factor homolog B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014810.2NP_001014810.1  protein YIF1B isoform b

      See identical proteins and their annotated locations for NP_001014810.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8L2QF93, A6J9Q0
      Conserved Domains (1) summary
      pfam03878
      Location:65298
      YIF1
    2. NM_198734.3NP_942029.2  protein YIF1B isoform a

      See identical proteins and their annotated locations for NP_942029.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8L2QF93, A6J9P9
      Related
      ENSRNOP00000045414.5, ENSRNOT00000044145.7
      Conserved Domains (1) summary
      pfam03878
      Location:73306
      YIF1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      93667113..93677381
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006228658.5XP_006228720.1  protein YIF1B isoform X1

      See identical proteins and their annotated locations for XP_006228720.1

      UniProtKB/Swiss-Prot
      Q6PEC3
      Conserved Domains (1) summary
      pfam03878
      Location:70303
      YIF1
    2. XM_006228660.5XP_006228722.1  protein YIF1B isoform X2

      See identical proteins and their annotated locations for XP_006228722.1

      UniProtKB/TrEMBL
      A0A0H2UHX7
      Related
      ENSRNOP00000027987.7, ENSRNOT00000027987.10
      Conserved Domains (1) summary
      pfam03878
      Location:43276
      YIF1
    3. XM_039104398.2XP_038960326.1  protein YIF1B isoform X2

      UniProtKB/TrEMBL
      A0A0H2UHX7
      Related
      ENSRNOP00000099435.1, ENSRNOT00000157810.1
      Conserved Domains (1) summary
      pfam03878
      Location:43276
      YIF1