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    CYP27A1 cytochrome P450 family 27 subfamily A member 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 610489, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CYP27A1provided by VGNC
    Official Full Name
    cytochrome P450 family 27 subfamily A member 1provided by VGNC
    Primary source
    VGNC:VGNC:50342
    See related
    Ensembl:ENSCAFG00845028313
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See CYP27A1 in Genome Data Viewer
    Location:
    chromosome: 37
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (25381673..25417125)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (26186269..26221708)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (25241871..25277345)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (25286426..25321814)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (25221115..25256548)

    Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867962 Neighboring gene tubulin tyrosine ligase like 4 Neighboring gene uncharacterized LOC111094371 Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 3 Neighboring gene uncharacterized LOC111094359 Neighboring gene Wnt family member 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in C21-steroid hormone biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to peptide hormone stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cholesterol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cortisol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glucocorticoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sterol 26-hydroxylase, mitochondrial
    Names
    cytochrome P450, family 27, subfamily A, polypeptide 1
    XP_038303901.1
    XP_038303902.1
    XP_038319771.1
    XP_038377876.1
    XP_038377877.1
    XP_038441836.1
    XP_038506073.1
    XP_038506074.1
    XP_853094.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051841.1 Reference ROS_Cfam_1.0

      Range
      25381673..25417125
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038447973.1 → XP_038303901.1  sterol 26-hydroxylase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0TQF8, A0A8I3PW50, A0A8P0NGR6
      Related
      ENSCAFP00845039275.1, ENSCAFT00845050090.1
      Conserved Domains (1) summary
      cl41757
      Location:92 → 528
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    2. XM_038447974.1 → XP_038303902.1  sterol 26-hydroxylase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0LTJ4
      Conserved Domains (1) summary
      cl41757
      Location:6 → 442
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049297.1 Alternate UMICH_Zoey_3.1

      Range
      25286426..25321814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038521948.1 → XP_038377876.1  sterol 26-hydroxylase, mitochondrial isoform X1

      Conserved Domains (1) summary
      cl41757
      Location:92 → 528
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    2. XM_038521949.1 → XP_038377877.1  sterol 26-hydroxylase, mitochondrial isoform X2

      Conserved Domains (1) summary
      cl41757
      Location:6 → 442
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

      Range
      25221115..25256548
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038650145.1 → XP_038506073.1  sterol 26-hydroxylase, mitochondrial isoform X1

      Conserved Domains (1) summary
      cl41757
      Location:92 → 528
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    2. XM_038650146.1 → XP_038506074.1  sterol 26-hydroxylase, mitochondrial isoform X2

      Conserved Domains (1) summary
      cl41757
      Location:6 → 442
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

      Range
      25241871..25277345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038585908.1 → XP_038441836.1  sterol 26-hydroxylase, mitochondrial isoform X3

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      26186269..26221708
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_848001.5 → XP_853094.4  sterol 26-hydroxylase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0TQF8, A0A8I3PW50, A0A8P0NGR6
      Conserved Domains (1) summary
      cl41757
      Location:92 → 528
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    2. XM_038463843.1 → XP_038319771.1  sterol 26-hydroxylase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0LTJ4
      Conserved Domains (1) summary
      cl41757
      Location:6 → 442
      cytochrome_P450; cytochrome P450 (CYP) superfamily
    Nucleotide Protein
    Heading Accession and Version

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