U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    HSD17B8 hydroxysteroid 17-beta dehydrogenase 8 [ Canis lupus familiaris (dog) ]

    Gene ID: 607895, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    HSD17B8provided by VGNC
    Official Full Name
    hydroxysteroid 17-beta dehydrogenase 8provided by VGNC
    Primary source
    VGNC:VGNC:41810
    See related
    Ensembl:ENSCAFG00845020603
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See HSD17B8 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (2998414..3000653)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (2748819..2751058)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (2822541..2824780)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (2666602..2668840)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (2747969..2750208)

    Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene collagen type XI alpha 2 chain Neighboring gene retinoid X receptor beta Neighboring gene solute carrier family 39 member 7 Neighboring gene microRNA mir-219-1 Neighboring gene ring finger protein 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in estrogen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    (3R)-3-hydroxyacyl-CoA dehydrogenase; estradiol 17-beta-dehydrogenase 8
    Names
    17-beta-HSD 8
    17-beta-hydroxysteroid dehydrogenase 8
    3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit
    3-oxoacyl-[acyl-carrier-protein] reductase
    Estradiol 17-beta-dehydrogenase 8
    KAR alpha subunit
    Testosterone 17-beta-dehydrogenase 8
    XP_005627255.2
    XP_013973838.1
    XP_013973839.1
    XP_038347413.1
    XP_038347414.1
    XP_038347415.1
    XP_038347416.1
    XP_038409636.1
    XP_038409637.1
    XP_038409638.1
    XP_038409639.1
    XP_038473499.1
    XP_038473500.1
    XP_038473501.1
    XP_038473502.1
    XP_038539107.1
    XP_038539108.1
    XP_038539109.1
    XP_038539110.1
    XP_851004.3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051816.1 Reference ROS_Cfam_1.0

      Range
      2998414..3000653
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038683179.1 → XP_038539107.1  estradiol 17-beta-dehydrogenase 8 isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:11 → 226
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. XM_038683182.1 → XP_038539110.1  estradiol 17-beta-dehydrogenase 8 isoform X4

      UniProtKB/Swiss-Prot
      Q5TJF5
      UniProtKB/TrEMBL
      A0A8C0JNZ3, A0A8C0QUD7
      Related
      ENSCAFP00845028421.1, ENSCAFT00845036315.1
      Conserved Domains (1) summary
      cd05333
      Location:11 → 258
      BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs

    3. XM_038683180.1 → XP_038539108.1  estradiol 17-beta-dehydrogenase 8 isoform X2

      Conserved Domains (1) summary
      cl21454
      Location:11 → 219
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. XM_038683181.1 → XP_038539109.1  estradiol 17-beta-dehydrogenase 8 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JNZ3
      Conserved Domains (1) summary
      cd05333
      Location:11 → 265
      BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049272.1 Alternate UMICH_Zoey_3.1

      Range
      2666602..2668840
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038491485.1 → XP_038347413.1  estradiol 17-beta-dehydrogenase 8 isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:11 → 226
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. XM_038491488.1 → XP_038347416.1  estradiol 17-beta-dehydrogenase 8 isoform X4

      Conserved Domains (1) summary
      cd05333
      Location:11 → 258
      BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs

    3. XM_038491486.1 → XP_038347414.1  estradiol 17-beta-dehydrogenase 8 isoform X2

      Conserved Domains (1) summary
      cl21454
      Location:11 → 219
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. XM_038491487.1 → XP_038347415.1  estradiol 17-beta-dehydrogenase 8 isoform X3

      Conserved Domains (1) summary
      cd05333
      Location:11 → 265
      BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

      Range
      2747969..2750208
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038617571.1 → XP_038473499.1  estradiol 17-beta-dehydrogenase 8 isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:11 → 226
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. XM_038617574.1 → XP_038473502.1  estradiol 17-beta-dehydrogenase 8 isoform X4

      Conserved Domains (1) summary
      cd05333
      Location:11 → 258
      BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs

    3. XM_038617572.1 → XP_038473500.1  estradiol 17-beta-dehydrogenase 8 isoform X2

      Conserved Domains (1) summary
      cl21454
      Location:11 → 219
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. XM_038617573.1 → XP_038473501.1  estradiol 17-beta-dehydrogenase 8 isoform X3

      Conserved Domains (1) summary
      cd05333
      Location:11 → 265
      BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

      Range
      2822541..2824780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038553708.1 → XP_038409636.1  estradiol 17-beta-dehydrogenase 8 isoform X1

    2. XM_038553711.1 → XP_038409639.1  estradiol 17-beta-dehydrogenase 8 isoform X4

      UniProtKB/TrEMBL
      A0A8C0JNZ3

    3. XM_038553709.1 → XP_038409637.1  estradiol 17-beta-dehydrogenase 8 isoform X2

    4. XM_038553710.1 → XP_038409638.1  estradiol 17-beta-dehydrogenase 8 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JNZ3

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      2748819..2751058
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014118363.3 → XP_013973838.1  estradiol 17-beta-dehydrogenase 8 isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:11 → 226
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. XM_845911.6 → XP_851004.3  estradiol 17-beta-dehydrogenase 8 isoform X4

      UniProtKB/TrEMBL
      A0A8C0JNZ3, A0A8C0TC64, A0A8P0S6V8
      Conserved Domains (1) summary
      cd05333
      Location:11 → 258
      BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs

    3. XM_014118364.3 → XP_013973839.1  estradiol 17-beta-dehydrogenase 8 isoform X2

      Conserved Domains (1) summary
      cl21454
      Location:11 → 219
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. XM_005627198.4 → XP_005627255.2  estradiol 17-beta-dehydrogenase 8 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JNZ3
      Conserved Domains (1) summary
      cd05333
      Location:11 → 265
      BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5TJF5.1 GenPept UniProtKB/Swiss-Prot:Q5TJF5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials